Protein: XRS2
DNA repair protein XRS2

Gene: XRS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 48
UniProt ID: P33301

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0003677 - DNA binding
GO:0003691 - double-stranded telomeric DNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

751039

ATM
Serine/threonine-protein kinase TEL1

7

1

Small-scale

0.740

High

745515

MRE11
Double-strand break repair protein MRE11

34

0

Small-scale

0.737

High

555244

RAD50
DNA repair protein RAD50

11

0

Small-scale

0.723

High

751050

XRCC4
Non-homologous end-joining factor LIF1

6

0

Small-scale

0.702

High

751049

COM1
DNA endonuclease SAE2

4

0

Small-scale

0.663

High

364444

CDK1
Cyclin-dependent kinase 1

1

0

Small-scale

0.614

High

751041

KSP1
Serine/threonine-protein kinase KSP1

1

0

High-throughput

0.613

High

751035

XRS2
DNA repair protein XRS2

1

0

Small-scale

0.586

High

751054

RIF2
Protein RIF2

2

0

Small-scale

0.569

High

639488

RE107
Recombination protein 107

2

0

Small-scale

0.565

High

751047

SSB2
Ribosome-associated molecular chaperone SSB2

2

1

High-throughput

0.552

High

647737

RFA1
Replication factor A protein 1

1

0

Small-scale

0.529

High

486768

CDC16
Anaphase-promoting complex subunit CDC16

1

0

High-throughput

0.513

High

568923

INO4
Protein INO4

1

0

High-throughput

0.513

High

751043

REV7
DNA polymerase zeta processivity subunit

1

0

Small-scale

0.504

High

751042

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

1

Small-scale

0.501

High

751044

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.493

High

381045

H2B1
Histone H2B.1

1

1

High-throughput

0.479

High

381471

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

751040

PCH2
Pachytene checkpoint protein 2

1

0

Small-scale

0.460

High

706641

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

751037

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

751048

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

751052

ACT
Actin

1

0

High-throughput

0.458

High

751053

H3
Histone H3

1

0

Small-scale

0.458

High

751058

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

523483

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526283

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

544310

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

741264

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

392484

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

726893

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

751051

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.426

High

510344

HSP77
Import motor subunit, mitochondrial

1

1

High-throughput

0.407

High

751045

HSP7E
Heat shock protein SSC3, mitochondrial

1

1

High-throughput

0.407

High

751056

SMT3
Ubiquitin-like protein SMT3

1

0

Small-scale

0.391

High

470641

ERG20
Farnesyl pyrophosphate synthase

1

0

High-throughput

0.279

Low

751036

AHP1
Peroxiredoxin AHP1

1

0

High-throughput

0.279

Low

751038

YBR3
Uncharacterized protein YBR063C

1

0

High-throughput

0.279

Low

751057

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.279

Low

405068

LEU3
3-isopropylmalate dehydrogenase

1

0

High-throughput

0.261

Low

555051

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

592141

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

751055

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

High-throughput

0.261

Low

541151

SYLM
Leucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.249

Low

577078

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

751046

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025