Protein: BRE2
COMPASS component BRE2 (Brefeldin-A sensitivity protein 2) (COMPASS protein 60) (Complex proteins associated with SET1 protein BRE2) (Set1C component BRE2)

Gene: BRE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 43
UniProt ID: P43132

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0031509 - subtelomeric heterochromatin formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

805549

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

23

12

Small-scale

0.768

High

793860

SWD3
COMPASS component SWD3

14

5

Small-scale

0.760

High

845936

SPP1
COMPASS component SPP1

13

5

Small-scale

0.759

High

813665

SWD1
COMPASS component SWD1

12

8

Small-scale

0.758

High

781145

SWD2
COMPASS component SWD2

10

7

Small-scale

0.753

High

845937

SDC1
COMPASS component SDC1

16

0

Small-scale

0.731

High

798405

SHG1
COMPASS component SHG1

7

0

Small-scale

0.714

High

402037

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

1

Small-scale

0.601

High

757334

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

Small-scale

0.559

High

545282

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

438537

UBC2
Ubiquitin-conjugating enzyme E2 2

1

1

Small-scale

0.515

High

845938

GIS1
Transcriptional activator/repressor GIS1

1

3

High-throughput

0.479

High

845940

CORO
Coronin-like protein

1

3

High-throughput

0.470

High

435170

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

707408

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

709826

BMH1
Protein BMH1

1

0

High-throughput

0.458

High

845939

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

670849

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

741801

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

742880

HSP79
Heat shock protein homolog SSE2

1

2

High-throughput

0.445

High

811335

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

845932

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.445

High

798561

HSM3
DNA mismatch repair protein HSM3

1

0

High-throughput

0.438

High

845931

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

392911

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

845935

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.426

High

845934

UBC7
Ubiquitin-conjugating enzyme E2 7

1

1

High-throughput

0.417

High

814217

RV167
Reduced viability upon starvation protein 167

1

0

High-throughput

0.269

Low

825404

PRK1
Actin-regulating kinase PRK1

1

0

High-throughput

0.269

Low

845941

ERFB
Palmitoyltransferase ERF2

1

0

High-throughput

0.269

Low

704685

PRR1
Serine/threonine-protein kinase PRR1

1

0

High-throughput

0.261

Low

365085

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.249

Low

383761

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

436027

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

441976

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

455122

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

513071

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

531348

METK1
S-adenosylmethionine synthase 1

1

0

Small-scale

0.249

Low

790209

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

Small-scale

0.249

Low

812410

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

845930

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.249

Low

845933

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

845942

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025