Protein: HSM3
DNA mismatch repair protein HSM3 (Enhanced spontaneous mutability protein 3)

Gene: HSM3
Organism: Saccharomyces cerevisiae S288C
Interactions: 58
UniProt ID: P38348

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006298 - mismatch repair
GO:0044183 - protein folding chaperone

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

750929

PRS7
26S proteasome regulatory subunit 7 homolog

14

2

Small-scale

0.986

High

798558

PRS4
26S proteasome regulatory subunit 4 homolog

7

2

Small-scale

0.958

High

798570

PRS8
26S proteasome regulatory subunit 8 homolog

7

2

Small-scale

0.956

High

750641

PRS6A
26S proteasome regulatory subunit 6A

11

0

Small-scale

0.926

High

798567

PRS10
26S proteasome subunit RPT4

3

2

Small-scale

0.848

High

750831

PRS6B
26S proteasome regulatory subunit 6B homolog

8

1

Small-scale

0.747

High

798552

RPN1
26S proteasome regulatory subunit RPN1

9

1

Small-scale

0.746

High

798578

RPN5
26S proteasome regulatory subunit RPN5

5

1

Small-scale

0.709

High

798572

RPN9
26S proteasome regulatory subunit RPN9

7

0

Small-scale

0.709

High

798566

RPN14
26S proteasome regulatory subunit RPN14

6

0

Small-scale

0.698

High

798565

PSD10
Probable 26S proteasome regulatory subunit p28

6

0

Small-scale

0.693

High

740150

RPN2
26S proteasome regulatory subunit RPN2

4

1

Small-scale

0.683

High

738298

RPN12
26S proteasome regulatory subunit RPN12

5

0

Small-scale

0.676

High

798553

RPN10
26S proteasome regulatory subunit RPN10

4

0

Small-scale

0.653

High

314865

SEM1
26S proteasome complex subunit SEM1

4

0

Small-scale

0.648

High

150280

RPN13
26S proteasome regulatory subunit RPN13

3

0

Small-scale

0.622

High

798574

RPN7
26S proteasome regulatory subunit RPN7

2

1

Small-scale

0.612

High

798562

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

Small-scale

0.601

High

798551

HSM3
DNA mismatch repair protein HSM3

1

0

Small-scale

0.586

High

382070

H4
Histone H4

2

0

High-throughput

0.563

High

798554

HAT2
Histone acetyltransferase type B subunit 2

2

0

High-throughput

0.563

High

798577

PSH1
RING finger protein PSH1

2

0

High-throughput

0.563

High

798579

HAT1
Histone acetyltransferase type B catalytic subunit

2

0

High-throughput

0.563

High

798580

HIF1
HAT1-interacting factor 1

2

0

High-throughput

0.563

High

544696

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

721253

PSB5
Proteasome subunit beta type-5

2

0

Small-scale

0.551

High

645159

PSB4
Proteasome subunit beta type-4

1

1

Small-scale

0.500

High

574672

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

636655

PSA1
Proteasome subunit alpha type-1

1

1

Small-scale

0.479

High

636568

PSA7
Probable proteasome subunit alpha type-7

1

0

Small-scale

0.458

High

706958

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

763275

SGS1
ATP-dependent helicase SGS1

1

0

High-throughput

0.458

High

792012

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.458

High

798568

CAF40
Protein CAF40

1

0

High-throughput

0.458

High

798569

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

798573

PDS5
Sister chromatid cohesion protein PDS5

1

0

High-throughput

0.458

High

523787

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526560

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

741480

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

747328

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.445

High

798556

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

798563

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.445

High

657081

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.438

High

743455

SEC17
Alpha-soluble NSF attachment protein

1

0

High-throughput

0.438

High

798559

GTS1
Protein GTS1

1

0

High-throughput

0.438

High

798561

BRE2
COMPASS component BRE2

1

0

High-throughput

0.438

High

798576

SOG2
Leucine-rich repeat-containing protein SOG2

1

0

High-throughput

0.438

High

579304

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.426

High

753337

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.426

High

798557

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.426

High

798564

RL38
Large ribosomal subunit protein eL38

1

0

High-throughput

0.426

High

798571

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

798575

RPN8
26S proteasome regulatory subunit RPN8

6

0

Small-scale

0.379

High

798555

RPN3
26S proteasome regulatory subunit RPN3

5

0

Small-scale

0.369

High

798581

RPN6
26S proteasome regulatory subunit RPN6

5

0

Small-scale

0.369

High

574882

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

798560

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025