Protein: SC61G
Protein transport protein SSS1 (Sec61 complex subunit SSS1) (Sec61 complex subunit gamma) (Ssh1 complex subunit SSS1) (Ssh1 complex subunit gamma)

Gene: SC61G, SSS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 42
UniProt ID: P35179

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005637 - nuclear inner membrane
GO:0005783 - endoplasmic reticulum
GO:0005784 - Sec61 translocon complex
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748326

SC61A
Protein transport protein SEC61

10

2

Small-scale

0.973

High

763160

SC6B1
Protein transport protein SBH1

6

1

Small-scale

0.929

High

763148

SSH1
Sec sixty-one protein homolog

3

2

Small-scale

0.849

High

577092

SEC63
Protein translocation protein SEC63

5

1

Small-scale

0.694

High

641362

SEC62
Translocation protein SEC62

3

0

Small-scale

0.622

High

754610

OSTB
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1

2

0

Small-scale

0.619

High

763164

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

2

0

Small-scale

0.601

High

763161

SC6B2
Protein transport protein SBH2

1

1

Small-scale

0.575

High

754384

SEC66
Translocation protein SEC66

2

0

Small-scale

0.547

High

763153

SEC72
Translocation protein SEC72

2

0

Small-scale

0.547

High

763156

OST1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

Small-scale

0.543

High

763171

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST4

1

0

Small-scale

0.543

High

618857

GAP1
General amino-acid permease GAP1

1

0

Small-scale

0.529

High

763169

NPC1
NPC intracellular sterol transporter 1-related protein 1

1

0

Small-scale

0.529

High

737559

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.518

High

763167

GUP2
Membrane-bound O-acyltransferase GUP2

1

0

High-throughput

0.518

High

763152

ERP2
Protein ERP2

1

0

High-throughput

0.493

High

763170

YPR71
Uncharacterized membrane protein YPR071W

1

0

High-throughput

0.486

High

746786

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

754674

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

0

Small-scale

0.458

High

763147

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

763150

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

763159

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

763166

EXP1
ER export of PMA1 protein 1

1

0

High-throughput

0.458

High

763172

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.458

High

763149

SIC1
Protein SIC1

1

0

High-throughput

0.282

High

763163

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.282

High

367235

ATP6
ATP synthase subunit a

1

0

Small-scale

0.249

Low

579158

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

632076

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

0

Small-scale

0.249

Low

677341

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

750617

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

750919

PRS7
26S proteasome regulatory subunit 7 homolog

1

0

Small-scale

0.249

Low

763146

ATG8
Autophagy-related protein 8

1

0

High-throughput

0.249

Low

763151

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

763157

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

763158

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

0

High-throughput

0.249

Low

763162

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.249

Low

763165

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.249

Low

763168

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low

763154

SLX8
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX8

1

0

High-throughput

0.238

Low

763155

SSB2
Ribosome-associated molecular chaperone SSB2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025