Protein: SYC
Cysteine--tRNA ligase (EC 6.1.1.16) (Cysteinyl-tRNA synthetase) (CysRS)

Gene: SYC, YNL247W
Organism: Saccharomyces cerevisiae S288C
Interactions: 34
UniProt ID: P53852

Gene Ontology (top 5):
GO:0004817 - cysteine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

923915

SYC
Cysteine--tRNA ligase

3

4

Small-scale

0.814

High

545794

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

676230

MAS5
Mitochondrial protein import protein MAS5

1

3

High-throughput

0.536

High

791979

PUR92
Bifunctional purine biosynthesis protein ADE17 [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase

1

0

High-throughput

0.518

High

783496

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.515

High

923919

HOSM
Homocitrate synthase, mitochondrial

1

1

High-throughput

0.515

High

641439

RCC1
Guanine nucleotide exchange factor SRM1

1

0

High-throughput

0.493

High

725930

PSK1
Serine/threonine-protein kinase PSK1

1

0

High-throughput

0.493

High

806485

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.493

High

368915

SYMC
Methionine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.479

High

581890

SYKC
Lysine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

709908

BMH1
Protein BMH1

1

2

High-throughput

0.479

High

795475

ATG8
Autophagy-related protein 8

1

7

High-throughput

0.479

High

812537

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

835811

MMM1
Maintenance of mitochondrial morphology protein 1

1

1

High-throughput

0.479

High

850129

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

922676

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.479

High

644689

ATP12
Protein ATP12, mitochondrial

1

0

High-throughput

0.458

High

921067

SPC98
Spindle pole body component SPC98

1

0

High-throughput

0.458

High

527342

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

597234

BIP
Endoplasmic reticulum chaperone BiP

1

1

High-throughput

0.445

High

626841

HSP60
Heat shock protein 60, mitochondrial

1

3

High-throughput

0.445

High

819422

SSB2
Ribosome-associated molecular chaperone SSB2

1

5

High-throughput

0.445

High

823628

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.445

High

923916

PFD4
Prefoldin subunit 4

1

1

High-throughput

0.445

High

707818

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

736392

MET4
Transcriptional activator of sulfur metabolism MET4

1

1

High-throughput

0.437

High

795132

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

923305

DUS1
tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]

1

1

High-throughput

0.437

High

923917

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.437

High

923918

YMC0
Uncharacterized protein YML020W

1

1

High-throughput

0.437

High

923920

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.437

High

780883

STB6
Protein STB6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025