Protein: PRTB
Cerevisin (EC 3.4.21.48) (Proteinase YSCB) (Vacuolar protease B) (PrB)

Gene: PRTB, PRB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 66
UniProt ID: P09232

Gene Ontology (top 5):
GO:0000324 - fungal-type vacuole
GO:0000328 - fungal-type vacuole lumen
GO:0000425 - pexophagy
GO:0004252 - serine-type endopeptidase activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

448472

HSP71
Heat shock protein SSA1

5

5

High-throughput

0.635

High

365609

HSP82
ATP-dependent molecular chaperone HSP82

3

5

High-throughput

0.585

High

448475

SYQ
Glutamine--tRNA ligase

2

1

High-throughput

0.549

High

448524

CDC53
Cell division control protein 53

2

2

High-throughput

0.549

High

448489

MKK2
MAP kinase kinase MKK2/SSP33

1

2

High-throughput

0.536

High

448512

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.515

High

419764

SNF1
Carbon catabolite-derepressing protein kinase

1

1

High-throughput

0.489

High

439605

SPS1
Sporulation-specific protein 1

1

1

High-throughput

0.489

High

448481

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

1

High-throughput

0.489

High

448504

COPB2
Coatomer subunit beta'

1

2

High-throughput

0.489

High

448511

COPA
Coatomer subunit alpha

1

2

High-throughput

0.489

High

448513

CBK1
Serine/threonine-protein kinase CBK1

1

1

High-throughput

0.489

High

448471

IPB2
Protease B inhibitor 2

1

0

High-throughput

0.458

High

448496

IMB2
Importin subunit beta-2

1

1

Small-scale

0.457

High

448476

SEC63
Protein translocation protein SEC63

1

2

Small-scale

0.439

High

389670

CDC25
Cell division control protein 25

1

2

High-throughput

0.437

High

448477

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.437

High

448480

PDI
Protein disulfide-isomerase

1

3

High-throughput

0.437

High

448485

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

448488

EUG1
Protein disulfide-isomerase EUG1

1

3

High-throughput

0.437

High

448491

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

2

High-throughput

0.437

High

448495

AKL1
Serine/threonine-protein kinase AKL1

1

2

High-throughput

0.437

High

448501

RSP5
E3 ubiquitin-protein ligase RSP5

1

2

High-throughput

0.437

High

448505

RIM15
Serine/threonine-protein kinase RIM15

1

3

High-throughput

0.437

High

448516

TOM1
E3 ubiquitin-protein ligase TOM1

1

2

High-throughput

0.437

High

448518

SEC13
Protein transport protein SEC13

1

1

High-throughput

0.437

High

448527

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.437

High

448473

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.407

High

448474

SSB1
Ribosome-associated molecular chaperone SSB1

1

4

High-throughput

0.407

High

448482

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.407

High

448502

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.407

High

448517

GCN5
Histone acetyltransferase GCN5

1

1

High-throughput

0.407

High

448498

SAF1
SCF-associated factor 1

3

0

Small-scale

0.342

High

448508

SKP1
Suppressor of kinetochore protein 1

2

0

High-throughput

0.313

High

448499

CRP1
Cruciform DNA-recognizing protein 1 [Cleaved into: CRP1 short N-terminal subpeptide; CRP1 short C-terminal subpeptide]

2

0

High-throughput

0.298

High

448479

HPR1
THO complex subunit HPR1

1

0

High-throughput

0.279

Low

448487

NTH1
Endonuclease III homolog 1

1

0

High-throughput

0.279

Low

448497

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.279

Low

448503

MET18
DNA repair/transcription protein MET18/MMS19

1

0

High-throughput

0.279

Low

448528

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.279

Low

448529

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.279

Low

448507

INP52
Polyphosphatidylinositol phosphatase INP52

1

0

High-throughput

0.269

Low

448483

PBN1
Protein PBN1

1

0

Small-scale

0.265

Low

448506

LSM1
Sm-like protein LSm1

1

0

High-throughput

0.265

Low

448515

H3
Histone H3

1

0

Small-scale

0.261

Low

448526

RIO1
Serine/threonine-protein kinase RIO1

1

0

Small-scale

0.251

Low

375215

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

448478

SEC2
Rab guanine nucleotide exchange factor SEC2

1

0

High-throughput

0.249

Low

448484

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.249

Low

448486

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

448492

SMY2
Protein SMY2

1

0

High-throughput

0.249

Low

448493

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.249

Low

448494

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.249

Low

448500

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.249

Low

448509

YG34
Uncharacterized protein YGR122W

1

0

High-throughput

0.249

Low

448510

ERV29
ER-derived vesicles protein ERV29

1

0

High-throughput

0.249

Low

448514

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

448519

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

448520

HBT1
Protein HBT1

1

0

High-throughput

0.249

Low

448522

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

448523

TCO89
Target of rapamycin complex 1 subunit TCO89

1

0

High-throughput

0.249

Low

448525

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.249

Low

448530

NAA25
N-terminal acetyltransferase B complex subunit MDM20

1

0

High-throughput

0.249

Low

448531

HAA1
Transcriptional activator HAA1

1

0

High-throughput

0.249

Low

448490

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.238

Low

448521

RBX1
RING-box protein HRT1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024