Protein: IES1
Ino eighty subunit 1

Gene: IES1
Organism: Saccharomyces cerevisiae S288C
Interactions: 74
UniProt ID: P43579

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

849881

INO80
Chromatin-remodeling ATPase INO80

16

1

Small-scale

0.761

High

849890

NHP10
Non-histone protein 10

6

1

Small-scale

0.730

High

849904

RUVB2
RuvB-like protein 2

5

1

Small-scale

0.714

High

849892

RUVB1
RuvB-like protein 1

5

1

Small-scale

0.712

High

849903

ARP8
Actin-like protein ARP8

4

1

Small-scale

0.691

High

849884

ARP5
Actin-related protein 5

3

1

High-throughput

0.662

High

849900

IES4
Ino eighty subunit 4

4

0

Small-scale

0.653

High

849888

ARP4
Actin-related protein 4

3

1

Small-scale

0.650

High

817700

IES5
Ino eighty subunit 5

3

0

High-throughput

0.634

High

849886

ACT
Actin

3

0

Small-scale

0.628

High

820290

IES2
Ino eighty subunit 2

3

0

High-throughput

0.622

High

763339

TAF14
Transcription initiation factor TFIID subunit 14

3

0

Small-scale

0.613

High

739397

ZUO1
Zuotin

2

1

High-throughput

0.588

High

849902

IES3
Ino eighty subunit 3

2

0

High-throughput

0.576

High

579599

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.571

High

804243

SSZ1
Ribosome-associated complex subunit SSZ1

2

0

High-throughput

0.563

High

826592

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

526984

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

707424

TF2B
Transcription initiation factor IIB

2

0

High-throughput

0.551

High

545301

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

419780

H2A2
Histone H2A.2

1

1

High-throughput

0.515

High

713624

EF1G1
Elongation factor 1-gamma 1

1

1

High-throughput

0.515

High

779073

EF1G2
Elongation factor 1-gamma 2

1

1

High-throughput

0.515

High

657101

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.493

High

849887

H3
Histone H3

1

0

Small-scale

0.480

High

392918

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.479

High

419448

H2A1
Histone H2A.1

1

1

Small-scale

0.479

High

849895

SWR1
Helicase SWR1

1

1

Small-scale

0.479

High

382169

H4
Histone H4

1

0

High-throughput

0.458

High

647790

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

739156

PRP19
Pre-mRNA-processing factor 19

1

0

Small-scale

0.458

High

739887

RPD3
Histone deacetylase RPD3

1

0

Small-scale

0.458

High

743838

IES6
Chromatin-remodeling complex subunit IES6

1

0

High-throughput

0.458

High

745784

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

763925

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

777069

BDF1
Bromodomain-containing factor 1

1

0

Small-scale

0.458

High

792701

GLRX7
Monothiol glutaredoxin-7

1

0

High-throughput

0.458

High

793429

ATR
Serine/threonine-protein kinase MEC1

1

0

Small-scale

0.458

High

800255

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.458

High

808843

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

849879

IES1
Ino eighty subunit 1

1

0

Small-scale

0.458

High

849885

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

849891

MSH6
DNA mismatch repair protein MSH6

1

0

Small-scale

0.458

High

849893

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

849894

DPB4
DNA polymerase epsilon subunit D

1

0

Small-scale

0.458

High

849898

IWS1
Transcription factor SPN1

1

0

Small-scale

0.458

High

849901

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

849906

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

524313

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

727122

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

741815

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

819063

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

849883

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

381145

H2B1
Histone H2B.1

1

0

High-throughput

0.426

High

547806

NHP6A
Non-histone chromosomal protein 6A

1

0

High-throughput

0.426

High

597184

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

671533

SWI4
Regulatory protein SWI4

1

0

High-throughput

0.426

High

676100

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

736666

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

781754

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

849896

NSE3
Non-structural maintenance of chromosome element 3

1

0

High-throughput

0.426

High

849899

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

849905

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

752407

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

849897

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

2

High-throughput

0.407

High

597493

EF3A
Elongation factor 3A

1

0

High-throughput

0.269

Low

794692

SRO77
Lethal(2) giant larvae protein homolog SRO77

1

0

High-throughput

0.269

Low

843223

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.249

Low

849882

PGA14
Hydrophilin YNL190W

1

0

High-throughput

0.249

Low

849889

RT10
Small ribosomal subunit protein uS10m

1

0

High-throughput

0.249

Low

358256

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

810712

TCPB
T-complex protein 1 subunit beta

1

0

High-throughput

0.232

Low

849880

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025