Protein: IES4
Ino eighty subunit 4

Gene: IES4
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: Q08561

Gene Ontology (top 5):
GO:0000722 - telomere maintenance via recombination
GO:0005634 - nucleus
GO:0006281 - DNA repair
GO:0006338 - chromatin remodeling
GO:0006355 - regulation of DNA-templated transcription

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917331

INO80
Chromatin-remodeling ATPase INO80

14

1

Small-scale

0.757

High

1044489

RUVB1
RuvB-like protein 1

5

1

Small-scale

0.706

High

1064496

ARP8
Actin-like protein ARP8

4

1

Small-scale

0.683

High

1064497

RUVB2
RuvB-like protein 2

4

1

Small-scale

0.683

High

763387

TAF14
Transcription initiation factor TFIID subunit 14

5

0

Small-scale

0.676

High

849900

IES1
Ino eighty subunit 1

4

0

Small-scale

0.653

High

1010216

ARP4
Actin-related protein 4

3

1

Small-scale

0.650

High

793460

ATR
Serine/threonine-protein kinase MEC1

2

1

Small-scale

0.629

High

817714

IES5
Ino eighty subunit 5

3

0

Small-scale

0.622

High

1064495

IES3
Ino eighty subunit 3

3

0

Small-scale

0.622

High

948678

ACT
Actin

3

0

Small-scale

0.613

High

925247

ARP5
Actin-related protein 5

2

1

Small-scale

0.584

High

743848

IES6
Chromatin-remodeling complex subunit IES6

2

0

Small-scale

0.559

High

820305

IES2
Ino eighty subunit 2

2

0

Small-scale

0.559

High

1042816

NHP10
Non-histone protein 10

2

0

Small-scale

0.559

High

646556

RAD53
Serine/threonine-protein kinase RAD53

1

0

Small-scale

0.537

High

793411

ATM
Serine/threonine-protein kinase TEL1

1

1

Small-scale

0.501

High

382393

H4
Histone H4

1

0

Small-scale

0.480

High

1051138

SWR1
Helicase SWR1

1

1

Small-scale

0.479

High

448342

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

0

High-throughput

0.458

High

739921

RPD3
Histone deacetylase RPD3

1

0

Small-scale

0.458

High

808925

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

932243

ORC1
Origin recognition complex subunit 1

1

0

High-throughput

0.458

High

1054863

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

1064494

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

1064499

H2AZ
Histone H2A.Z

1

0

Small-scale

0.458

High

924757

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

546565

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

736743

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

737654

HIR1
Protein HIR1

1

0

High-throughput

0.426

High

1064498

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

592545

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.269

Low

923886

GIS2
Zinc finger protein GIS2

1

0

High-throughput

0.249

Low

752828

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

863771

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025