Protein: IES3
Ino eighty subunit 3

Gene: IES3
Organism: Saccharomyces cerevisiae S288C
Interactions: 69
UniProt ID: Q12345

Gene Ontology (top 5):
GO:0000722 - telomere maintenance via recombination
GO:0000723 - telomere maintenance
GO:0000781 - chromosome, telomeric region
GO:0005634 - nucleus
GO:0006281 - DNA repair

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

917339

INO80
Chromatin-remodeling ATPase INO80

17

2

Small-scale

0.761

High

1084809

RUVB2
RuvB-like protein 2

5

1

Small-scale

0.714

High

1044512

RUVB1
RuvB-like protein 1

5

1

Small-scale

0.712

High

1042818

NHP10
Non-histone protein 10

6

0

Small-scale

0.701

High

1084808

ARP8
Actin-like protein ARP8

4

1

Small-scale

0.683

High

817715

IES5
Ino eighty subunit 5

4

0

High-throughput

0.670

High

925251

ARP5
Actin-related protein 5

3

1

Small-scale

0.656

High

743851

IES6
Chromatin-remodeling complex subunit IES6

3

0

Small-scale

0.622

High

1064495

IES4
Ino eighty subunit 4

3

0

Small-scale

0.622

High

763401

TAF14
Transcription initiation factor TFIID subunit 14

3

0

Small-scale

0.613

High

1010220

ARP4
Actin-related protein 4

2

1

High-throughput

0.601

High

820309

IES2
Ino eighty subunit 2

2

0

High-throughput

0.576

High

849902

IES1
Ino eighty subunit 1

2

0

High-throughput

0.576

High

381318

H2B1
Histone H2B.1

2

0

Small-scale

0.560

High

382420

H4
Histone H4

2

0

Small-scale

0.560

High

948698

ACT
Actin

2

0

Small-scale

0.559

High

528057

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.552

High

546801

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

742714

HSP7F
Heat shock protein homolog SSE1

2

3

High-throughput

0.552

High

1055009

SP382
Pre-mRNA-splicing factor SPP382

2

0

High-throughput

0.541

High

917001

BOL2
BolA-like protein 2

1

0

High-throughput

0.518

High

1064906

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

0

High-throughput

0.513

High

367153

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.489

High

452995

ATPA
ATP synthase subunit alpha, mitochondrial

1

2

High-throughput

0.489

High

603575

VATA
V-type proton ATPase catalytic subunit A

1

3

High-throughput

0.489

High

633585

SAR1
Small COPII coat GTPase SAR1

1

1

High-throughput

0.489

High

793465

ATR
Serine/threonine-protein kinase MEC1

1

1

Small-scale

0.479

High

1051140

SWR1
Helicase SWR1

1

2

Small-scale

0.479

High

814100

MTW1
Kinetochore-associated protein MTW1

1

0

High-throughput

0.460

High

647862

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

708573

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

739925

RPD3
Histone deacetylase RPD3

1

0

Small-scale

0.458

High

745916

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

764037

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

792710

GLRX7
Monothiol glutaredoxin-7

1

0

High-throughput

0.458

High

826417

MPH1
ATP-dependent DNA helicase MPH1

1

0

High-throughput

0.458

High

826945

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

1026868

CDC14
Tyrosine-protein phosphatase CDC14

1

0

Small-scale

0.458

High

1084261

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

481816

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

525593

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.445

High

805240

TRA1
SAGA complex/NuA4 acetyltransferase complex subunit TRA1

1

1

High-throughput

0.445

High

486360

TBA1
Tubulin alpha-1 chain

1

0

High-throughput

0.426

High

736756

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

781817

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

817990

IMB4
Importin subunit beta-4

1

0

High-throughput

0.426

High

1035353

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

0

High-throughput

0.426

High

1061386

RSC58
Chromatin structure-remodeling complex protein RSC58

1

0

High-throughput

0.426

High

1084810

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

592588

VATB
V-type proton ATPase subunit B

1

2

High-throughput

0.407

High

597581

EF3A
Elongation factor 3A

1

2

High-throughput

0.407

High

755196

GCN1
eIF-2-alpha kinase activator GCN1

1

1

High-throughput

0.407

High

849568

GCN20
Protein GCN20

1

1

High-throughput

0.407

High

536191

ARF1
ADP-ribosylation factor 1

1

0

High-throughput

0.279

Low

575540

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.279

Low

639094

VPS1
Vacuolar protein sorting-associated protein 1

1

0

High-throughput

0.279

Low

843237

ZIM17
Mitochondrial protein import protein ZIM17

1

0

High-throughput

0.249

Low

924162

PGA14
Hydrophilin YNL190W

1

0

High-throughput

0.249

Low

1041905

RT10
Small ribosomal subunit protein uS10m

1

0

High-throughput

0.249

Low

574946

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

358380

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.232

Low

365236

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

395022

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.232

Low

453851

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.232

Low

734234

EF2
Elongation factor 2

1

0

High-throughput

0.232

Low

752900

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

796198

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.232

Low

836969

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

863791

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025