Protein: HIR3
Histone transcription regulator 3

Gene: HIR3
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P47171

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000417 - HIR complex
GO:0003714 - transcription corepressor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

736676

ASF1
Histone chaperone ASF1

8

1

Small-scale

0.744

High

737639

HIR1
Protein HIR1

5

3

Small-scale

0.706

High

737678

HIR2
Protein HIR2

4

3

Small-scale

0.694

High

866255

HPC2
Histone promoter control protein 2

4

0

Small-scale

0.661

High

866254

H3
Histone H3

2

0

Small-scale

0.559

High

382197

H4
Histone H4

2

0

Small-scale

0.547

High

524455

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.536

High

866256

SML1
Ribonucleotide reductase inhibitor protein SML1

1

0

High-throughput

0.513

High

816660

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.486

High

707551

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

740986

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

745802

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

763935

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

826637

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.458

High

858438

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.458

High

865662

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

866253

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.458

High

866260

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

866262

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

527086

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

670893

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

741916

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

545453

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

676136

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

804278

SSZ1
Ribosome-associated complex subunit SSZ1

1

0

High-throughput

0.426

High

820424

RT106
Histone chaperone RTT106

1

0

High-throughput

0.426

High

866261

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

866258

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

2

High-throughput

0.407

High

688756

RFA2
Replication factor A protein 2

1

0

High-throughput

0.279

Low

518328

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.269

Low

866257

EIS1
Eisosome protein 1

1

0

High-throughput

0.269

Low

850415

ATG18
Autophagy-related protein 18

1

0

Small-scale

0.265

Low

470654

ERG20
Farnesyl pyrophosphate synthase

1

0

Small-scale

0.251

Low

864770

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.249

Low

866259

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

863637

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025