Protein: EIS1
Eisosome protein 1

Gene: EIS1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: Q05050

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005886 - plasma membrane
GO:0032126 - eisosome
GO:0070941 - eisosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

918688

PIL1
Sphingolipid long chain base-responsive protein PIL1

7

1

Small-scale

0.742

High

919258

YG3A
Uncharacterized protein YGR130C

5

17

Small-scale

0.703

High

1050322

LSP1
Sphingolipid long chain base-responsive protein LSP1

3

1

Small-scale

0.650

High

1046235

SEG1
Eisosome protein SEG1

3

0

Small-scale

0.622

High

546266

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.601

High

819791

SSB2
Ribosome-associated molecular chaperone SSB2

2

4

High-throughput

0.588

High

527670

HSP72
Heat shock protein SSA2

2

5

High-throughput

0.552

High

742388

HSP7F
Heat shock protein homolog SSE1

2

6

High-throughput

0.552

High

963716

H3
Histone H3

2

6

High-throughput

0.549

High

1050323

HSP42
Heat shock protein 42

2

0

High-throughput

0.528

High

760350

BMH2
Protein BMH2

1

2

High-throughput

0.515

High

751486

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

High-throughput

0.493

High

805637

LSM12
Protein LSM12

1

0

High-throughput

0.493

High

817954

IMB4
Importin subunit beta-4

1

0

High-throughput

0.493

High

809100

DUN1
DNA damage response protein kinase DUN1

1

8

High-throughput

0.489

High

359070

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

Small-scale

0.479

High

510817

HSP77
Import motor subunit, mitochondrial

1

5

High-throughput

0.479

High

624810

PMA2
Plasma membrane ATPase 2

1

1

High-throughput

0.479

High

672597

YCP4
Flavoprotein-like protein YCP4

1

1

Small-scale

0.479

High

680061

CDC48
Cell division control protein 48

1

2

High-throughput

0.479

High

795533

ATG8
Autophagy-related protein 8

1

3

High-throughput

0.479

High

826359

INP51
Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP51

1

3

Small-scale

0.479

High

1050324

PST2
Protoplast secreted protein 2

1

1

High-throughput

0.479

High

1050325

LAS17
Proline-rich protein LAS17

1

3

Small-scale

0.479

High

734206

EF2
Elongation factor 2

1

3

High-throughput

0.470

High

796719

RFC5
Replication factor C subunit 5

1

1

High-throughput

0.470

High

816554

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.470

High

924490

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.460

High

433292

RL17A
Large ribosomal subunit protein uL22A

1

0

Small-scale

0.458

High

436174

RS13
Small ribosomal subunit protein uS15

1

0

Small-scale

0.458

High

645535

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

647223

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

656876

KC12
Casein kinase I homolog 2

1

0

Small-scale

0.458

High

804827

PP2C7
Protein phosphatase 2C homolog 7, mitochondrial

1

0

High-throughput

0.458

High

814113

GIP4
GLC7-interacting protein 4

1

0

High-throughput

0.458

High

925052

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

925388

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

1046302

VMS1
tRNA endonuclease VMS1

1

0

High-throughput

0.458

High

1046694

EUC1
Transcription factor-like protein EUC1

1

0

Small-scale

0.458

High

1050319

HBT1
Protein HBT1

1

0

High-throughput

0.458

High

1050320

SGO1
Shugoshin

1

0

High-throughput

0.458

High

393326

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

525144

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

816403

HSP7E
Heat shock protein SSC3, mitochondrial

1

5

High-throughput

0.445

High

700146

PRP45
Pre-mRNA-processing protein 45

1

1

Small-scale

0.439

High

893113

KEL2
Kelch repeat-containing protein 2

1

10

High-throughput

0.439

High

382342

H4
Histone H4

1

5

High-throughput

0.437

High

503850

RL27A
Large ribosomal subunit protein eL27A

1

1

Small-scale

0.437

High

503956

RL27B
Large ribosomal subunit protein eL27B

1

1

Small-scale

0.437

High

708179

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

779349

CENPA
Histone H3-like centromeric protein CSE4

1

6

High-throughput

0.437

High

795213

NU170
Nucleoporin NUP170

1

2

High-throughput

0.437

High

1050321

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

394906

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

811395

CAJ1
Protein CAJ1

1

0

High-throughput

0.426

High

812261

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.426

High

863733

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

1050318

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

10

High-throughput

0.407

High

826832

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.305

High

866257

HIR3
Histone transcription regulator 3

1

0

High-throughput

0.269

Low

764155

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

812652

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

865751

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

1044458

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.249

Low

1050317

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025