Protein: SRPB
Signal recognition particle receptor subunit beta (SR-beta)

Gene: SRPB, SRP102
Organism: Saccharomyces cerevisiae S288C
Interactions: 50
UniProt ID: P36057

Gene Ontology (top 5):
GO:0005047 - signal recognition particle binding
GO:0005525 - GTP binding
GO:0005785 - signal recognition particle receptor complex
GO:0005789 - endoplasmic reticulum membrane
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748604

SRPR
Signal recognition particle receptor subunit alpha homolog

9

6

Small-scale

0.973

High

780439

SRPB
Signal recognition particle receptor subunit beta

1

17

Small-scale

0.734

High

748336

SC61A
Protein transport protein SEC61

2

3

High-throughput

0.561

High

618859

GAP1
General amino-acid permease GAP1

1

9

Small-scale

0.552

High

416693

CAN1
Arginine permease CAN1

1

12

High-throughput

0.541

High

554335

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.541

High

735818

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

3

High-throughput

0.541

High

745322

EMP24
Endosomal protein P24B

1

12

High-throughput

0.541

High

780440

MAL31
Maltose permease MAL31

1

5

High-throughput

0.541

High

780443

SSH1
Sec sixty-one protein homolog

1

3

High-throughput

0.541

High

780448

SUR2
Sphingolipid C4-hydroxylase SUR2

1

2

High-throughput

0.541

High

780450

ELO1
Fatty acid elongase 1

1

3

High-throughput

0.541

High

780454

EMP47
Protein EMP47

1

1

High-throughput

0.541

High

780459

ERG25
C-4 methylsterol oxidase ERG25

1

2

High-throughput

0.541

High

780460

MAL11
General alpha-glucoside permease

1

5

High-throughput

0.541

High

780461

TNA1
High-affinity nicotinic acid transporter

1

3

High-throughput

0.541

High

780463

OSTD
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit SWP1

1

1

High-throughput

0.541

High

780465

ERV41
ER-derived vesicles protein ERV41

1

6

High-throughput

0.541

High

780468

SAM3
S-adenosylmethionine permease SAM3

1

10

High-throughput

0.541

High

780471

TECR
Very-long-chain enoyl-CoA reductase

1

6

High-throughput

0.541

High

763789

CSG2
Mannosyl phosphorylinositol ceramide synthase regulatory protein CSG2

1

0

High-throughput

0.518

High

780442

YPC1
Alkaline ceramidase YPC1

1

0

High-throughput

0.518

High

780445

COS8
Protein COS8

1

0

High-throughput

0.518

High

780446

YHU0
UPF0641 membrane protein YHR140W

1

0

High-throughput

0.518

High

780447

CHS7
Chitin synthase export chaperone

1

0

High-throughput

0.518

High

780453

PMP2
Plasma membrane ATPase proteolipid 2

1

0

High-throughput

0.518

High

780455

GPI2
Phosphatidylinositol N-acetylglucosaminyltransferase GPI2 subunit

1

0

High-throughput

0.518

High

780456

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.518

High

780457

GPI8
GPI-anchor transamidase

1

0

High-throughput

0.518

High

780466

PMT7
Probable dolichyl-phosphate-mannose--protein mannosyltransferase 7

1

0

High-throughput

0.518

High

780467

YP264
Probable transport protein YPL264C

1

0

High-throughput

0.518

High

780470

POM33
Pore membrane protein of 33 kDa

1

0

High-throughput

0.518

High

780469

GET3
ATPase GET3

1

2

High-throughput

0.508

High

751819

SGE1
Protein SGE1

1

3

High-throughput

0.494

High

780458

AVT4
Vacuolar amino acid transporter 4

1

7

High-throughput

0.494

High

780444

SRP72
Signal recognition particle subunit SRP72

1

1

High-throughput

0.479

High

780462

UBC7
Ubiquitin-conjugating enzyme E2 7

1

12

High-throughput

0.457

High

486131

TBA1
Tubulin alpha-1 chain

1

15

High-throughput

0.445

High

647750

RFA1
Replication factor A protein 1

1

11

Small-scale

0.439

High

542959

CDC24
Cell division control protein 24

1

6

High-throughput

0.437

High

579197

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.437

High

755075

GCN1
eIF-2-alpha kinase activator GCN1

1

4

High-throughput

0.437

High

780451

IF4F2
Eukaryotic initiation factor 4F subunit p130

1

3

High-throughput

0.437

High

780452

IMB4
Importin subunit beta-4

1

6

High-throughput

0.437

High

523598

HSP71
Heat shock protein SSA1

1

9

High-throughput

0.407

High

780449

FET3
Iron transport multicopper oxidase FET3

1

0

High-throughput

0.282

High

780464

GAS3
Probable 1,3-beta-glucanosyltransferase GAS3

1

0

High-throughput

0.282

High

764054

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

780441

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025