Protein: PHS
Putative pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Pterin carbinolamine dehydratase) (PCD)

Gene: PHS, YHL018W
Organism: Saccharomyces cerevisiae S288C
Interactions: 33
UniProt ID: P38744

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0006729 - tetrahydrobiopterin biosynthetic process
GO:0008124 - 4-alpha-hydroxytetrahydrobiopterin dehydratase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

803225

PHS
Putative pterin-4-alpha-carbinolamine dehydratase

2

0

High-throughput

0.738

High

738636

EI2BB
Translation initiation factor eIF2B subunit beta

2

0

High-throughput

0.565

High

803228

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.513

High

484758

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

510460

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.458

High

554920

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

594940

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

737454

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

796913

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

700001

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

2

0

High-throughput

0.314

High

803234

MUK1
Protein MUK1

2

0

High-throughput

0.307

High

803233

IMA1
Importin subunit alpha

1

0

High-throughput

0.282

High

803227

RIO2
Serine/threonine-protein kinase RIO2

1

0

High-throughput

0.279

Low

798436

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.265

Low

803230

PAU12
Seripauperin-12

1

0

High-throughput

0.265

Low

803231

CAF40
Protein CAF40

1

0

High-throughput

0.265

Low

803236

HNT1
Adenosine 5'-monophosphoramidase HNT1

1

0

High-throughput

0.265

Low

803237

EUC1
Transcription factor-like protein EUC1

1

0

High-throughput

0.265

Low

803238

PSH1
RING finger protein PSH1

1

0

High-throughput

0.265

Low

509531

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

0

High-throughput

0.261

Low

803239

PRR2
Serine/threonine-protein kinase PRR2

1

0

High-throughput

0.261

Low

430841

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

0

High-throughput

0.249

Low

523837

HSP71
Heat shock protein SSA1

1

0

High-throughput

0.249

Low

553610

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.249

Low

677379

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

707006

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

793260

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

0

High-throughput

0.249

Low

803226

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

803229

SPC1
Signal peptidase complex subunit 1

1

0

High-throughput

0.249

Low

803235

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

803232

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

544751

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025