Protein: ERG2
C-8 sterol isomerase ERG2 (EC 5.-.-.-) (Delta-8--delta-7 sterol isomerase ERG2) (Ergosterol biosynthetic protein 2)

Gene: ERG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 37
UniProt ID: P32352

Gene Ontology (top 5):
GO:0000247 - C-8 sterol isomerase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0006696 - ergosterol biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

735302

ERG2
C-8 sterol isomerase ERG2

2

1

Small-scale

0.793

High

735303

ERG24
Delta(14)-sterol reductase ERG24

2

0

Small-scale

0.588

High

735310

ERG28
Ergosterol biosynthetic protein 28

2

0

Small-scale

0.588

High

668886

ERG6
Sterol 24-C-methyltransferase ERG6

1

0

Small-scale

0.518

High

735304

ERG1
Squalene epoxidase ERG1

1

0

Small-scale

0.518

High

735318

ERG25
C-4 methylsterol oxidase ERG25

1

0

Small-scale

0.518

High

735319

ERG26
Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating

1

0

Small-scale

0.518

High

735321

RTN1
Reticulon-like protein 1

1

2

High-throughput

0.479

High

735323

ENV10
SRP-independent targeting protein 2

1

1

High-throughput

0.479

High

454285

CARP
Saccharopepsin

1

0

High-throughput

0.458

High

726066

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

0

High-throughput

0.458

High

735306

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.458

High

735307

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

735309

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

0

High-throughput

0.458

High

735311

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

0

Small-scale

0.458

High

735312

ELO3
Fatty acid elongase 3

1

0

High-throughput

0.458

High

735313

APQ12
Nuclear membrane organization protein APQ12

1

0

High-throughput

0.458

High

735316

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.458

High

735320

GSF2
Glucose-signaling factor 2

1

0

High-throughput

0.458

High

735322

YOP1
Protein YOP1

1

0

High-throughput

0.458

High

528563

CP51
Lanosterol 14-alpha demethylase CYP51

1

0

Small-scale

0.438

High

526155

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.437

High

544136

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.437

High

735315

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

0

High-throughput

0.305

High

444455

DED1
ATP-dependent RNA helicase DED1

1

0

High-throughput

0.249

Low

579026

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.249

Low

646335

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.249

Low

647040

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.249

Low

670451

SIS1
Protein SIS1

1

0

High-throughput

0.249

Low

706469

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

709617

BMH1
Protein BMH1

1

0

High-throughput

0.249

Low

726829

HS104
Heat shock protein 104

1

0

High-throughput

0.249

Low

735305

PRS6A
26S proteasome regulatory subunit 6A

1

0

High-throughput

0.249

Low

735308

RPN10
26S proteasome regulatory subunit RPN10

1

0

High-throughput

0.249

Low

735314

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

735317

VATG
V-type proton ATPase subunit G

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025