Protein: ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2 (EC 2.4.1.132) (EC 2.4.1.257) (Asparagine-linked glycosylation protein 2) (GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase) (GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase) (GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase)

Gene: ALG2
Organism: Saccharomyces cerevisiae S288C
Interactions: 36
UniProt ID: P43636

Gene Ontology (top 5):
GO:0000009 - alpha-1,6-mannosyltransferase activity
GO:0000033 - alpha-1,3-mannosyltransferase activity
GO:0004378 - GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598515

ALG1
Chitobiosyldiphosphodolichol beta-mannosyltransferase

1

1

Small-scale

0.665

High

850936

PEX29
Peroxisomal membrane protein PEX29

1

0

High-throughput

0.486

High

554357

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

1

High-throughput

0.479

High

554435

HMDH2
3-hydroxy-3-methylglutaryl-coenzyme A reductase 2

1

1

High-throughput

0.479

High

726098

PMT2
Dolichyl-phosphate-mannose--protein mannosyltransferase 2

1

1

High-throughput

0.479

High

735848

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

Small-scale

0.479

High

754700

PMT1
Dolichyl-phosphate-mannose--protein mannosyltransferase 1

1

1

High-throughput

0.479

High

816197

SPF1
Endoplasmic reticulum transmembrane helix translocase

1

1

High-throughput

0.479

High

822305

ELO3
Fatty acid elongase 3

1

2

High-throughput

0.479

High

850933

SCS3
Acyl-coenzyme A diphosphatase SCS3

1

0

Small-scale

0.460

High

577159

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.458

High

636324

ACO1
Acyl-CoA desaturase 1

1

0

High-throughput

0.458

High

677109

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

678012

CWH43
Protein CWH43

1

0

High-throughput

0.458

High

735316

ERG2
C-8 sterol isomerase ERG2

1

0

High-throughput

0.458

High

735345

ERG3
Delta(7)-sterol 5(6)-desaturase ERG3

1

0

High-throughput

0.458

High

748609

SRPR
Signal recognition particle receptor subunit alpha homolog

1

0

High-throughput

0.458

High

754403

SEC66
Translocation protein SEC66

1

0

High-throughput

0.458

High

802485

LAG1
Ceramide synthase LAG1

1

0

High-throughput

0.458

High

829993

LCB2
Serine palmitoyltransferase 2

1

0

High-throughput

0.458

High

850932

HLJ1
Protein HLJ1

1

0

High-throughput

0.458

High

850939

CUE4
CUE domain-containing protein CUE4

1

0

High-throughput

0.458

High

850941

ERP4
Protein ERP4

1

0

High-throughput

0.458

High

850942

PGA3
Plasma membrane-associated coenzyme Q6 reductase PGA3

1

0

High-throughput

0.458

High

850935

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.457

High

524337

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.437

High

709841

BMH1
Protein BMH1

1

3

High-throughput

0.437

High

795061

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

850938

SXM1
Importin beta SMX1

1

1

High-throughput

0.437

High

734693

IMB3
Importin subunit beta-3

1

0

High-throughput

0.249

Low

758456

YKK0
Probable intramembrane protease YKL100C

1

0

High-throughput

0.249

Low

825699

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.249

Low

826604

DSN1
Kinetochore-associated protein DSN1

1

0

High-throughput

0.249

Low

850934

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.249

Low

850937

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

850940

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025