HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: POC1B (Q8TC44)
POC1 centriolar protein homolog B (Pix1) (Proteome of centriole protein 1B) (WD repeat-containing protein 51B)
Gene: POC1B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25011449
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005737 - cytoplasm GO:0005813 - centrosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 478
+	Hs
		1043114 CUL4A_HUMAN (10-768): 0: 791: 38.32		POC1B_HUMAN (1-478): 3.05e-145: 425: 100.00
+	Hs
		1043469 CUL4B_HUMAN (5-768): 0: 779: 36.77		POC1B_HUMAN (1-478): 3.05e-145: 425: 100.00
+	Hs
		197016 CUL3_HUMAN (1-768): 0: 951: 100.00		PRP4_HUMAN (214-438): 4.93e-33: 133: 16.17
+	Hs
		152875 CUL3_HUMAN (1-768): 0: 951: 100.00		APAF_HUMAN (4-170): 2.89e-28: 121: 21.14
+	Hs
		903207 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	Hs
		921555 CUL3_HUMAN (1-768): 0: 951: 100.00		GBB2_HUMAN (180-358): 2.7e-19: 90.8: 16.39
+	Hs
		1041647 CUL3_HUMAN (1-768): 0: 951: 100.00		TAF5_HUMAN (155-300): 3.58e-10: 64.3: 30.41
+	Hs
		1042655 CUL3_HUMAN (1-768): 0: 951: 100.00		NLE1_HUMAN (358-439): 1.89e-09: 61.7: 8.33
+	Hs
		1043499 CUL4B_HUMAN (5-768): 0: 779: 36.77		FBXW7_HUMAN (213-440): 6.09e-42: 160: 17.47
+	Hs
		560878 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB3_HUMAN (6-172): 5.92e-35: 135: 24.71
+	Hs
		1043234 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB4_HUMAN (6-172): 2.46e-34: 133: 25.88
+	Hs
		152876 CUL4B_HUMAN (5-768): 0: 779: 36.77		APAF_HUMAN (4-170): 2.89e-28: 121: 21.14
+	Hs
		903208 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	Hs
		1043085 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5B_HUMAN (299-443): 8.32e-24: 103: 6.12
+	Hs
		792982 CUL4A_HUMAN (10-768): 0: 791: 38.32		LIS1_HUMAN (313-443): 2.88e-21: 97.5: 9.77
+	Hs
		903209 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5_HUMAN (300-443): 5.44e-25: 107: 7.53
+	Hs
		1043157 CUL4A_HUMAN (10-768): 0: 791: 38.32		SNR40_HUMAN (312-458): 2.16e-19: 91.4: 9.93
+	Hs
		1043441 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5B_HUMAN (299-443): 8.32e-24: 103: 6.12
+	Hs
		921556 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB2_HUMAN (180-358): 2.7e-19: 90.8: 16.39
+	Hs
		245601 CUL4B_HUMAN (5-768): 0: 779: 36.77		TBL1X_HUMAN (314-444): 7.07e-13: 72.5: 6.12