HitPredict

Interactor 1: CKAP5 (Q14008)
Cytoskeleton-associated protein 5 (Colonic and hepatic tumor overexpressed gene protein) (Ch-TOG)
Gene: CKAP5

Interactor 2: TACC3 (Q9Y6A5)
Transforming acidic coiled-coil-containing protein 3 (ERIC-1)
Gene: TACC3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.697

Property	Details
Experiments	26496610, 33961781, 20360068, 21297582
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007052 - mitotic spindle organization GO:0051301 - cell division
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2032 Hs			1 838
+	Hs
		264045 CKAP5_HUMAN (1-2032): 0: 1608: 100.00		TACC1_HUMAN (127-837): 2.57e-36: 149: 26.70
+	Hs
		311807 CKAP5_HUMAN (1-2032): 0: 1608: 100.00		TACC2_HUMAN (74-837): 4.81e-35: 146: 20.10
+	Hs
		91405 CKAP5_HUMAN (1-2032): 0: 1608: 100.00		E7EMZ9_HUMAN (74-837): 1.72e-30: 132: 19.22
+	Dm
		90876 E1JIM4_DROME (1-1992): 0: 1229: 38.36		Q86BB4_DROME (617-832): 4.61e-28: 115: 25.46
+	Hs
		254588 CLAP2_HUMAN (1086-1611): 1.06e-43: 177: 13.65		DCTN1_HUMAN (515-836): 6.94e-39: 158: 16.86
+	Hs
		297835 CLAP1_HUMAN (366-1077): 2e-13: 78.6: 8.85		K0754_HUMAN (125-838): 2.23e-54: 207: 15.08
+	Hs
		1051342 CLAP1_HUMAN (366-1077): 2e-13: 78.6: 8.85		DCTN1_HUMAN (515-836): 6.94e-39: 158: 16.86