HitPredict

Interactor 1: SH21A (O88890)
SH2 domain-containing protein 1A (Signaling lymphocytic activation molecule-associated protein) (SLAM-associated protein) (T-cell signal transduction molecule SAP)
Gene: Sh2d1a

Interactor 2: SLAF1 (Q9QUM4)
Signaling lymphocytic activation molecule (SLAM family member 1) (CD antigen CD150)
Gene: Slamf1

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	19151721, 12545173, 11477403, 16847311
Identification Methods	anti bait coimmunoprecipitation, pull down, coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0002250 - adaptive immune response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Mm			1 343
+	Mm
		1424431 SHIP1_MOUSE (5-126): 1.9e-37: 135: 36.89		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Mm
		813534 FYN_MOUSE (1-124): 7.69e-37: 132: 18.66		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Mm
		1192885 SH21C_MOUSE (5-105): 4.38e-38: 126: 42.57		SLAF1_MOUSE (1-343): 1.66e-91: 278: 100.00
+	Hs
		440537 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		SLAF1_HUMAN (1-343): 2.33e-80: 250: 59.77
+	Hs
		486690 FGR_HUMAN (1-124): 2.31e-36: 131: 22.14		SLAF1_HUMAN (1-343): 2.33e-80: 250: 59.77
+	Hs
		440172 LCK_HUMAN (1-124): 9.23e-41: 143: 20.77		SLAF6_HUMAN (13-338): 3.25e-63: 205: 19.35
+	Hs
		187404 SHIP2_HUMAN (3-120): 7.99e-40: 142: 42.37		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		440719 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		557456 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		CD244_HUMAN (39-339): 6.37e-60: 198: 21.68
+	Hs
		840990 ABL2_HUMAN (1-124): 3.69e-35: 129: 25.78		SLAF5_HUMAN (7-342): 2.48e-48: 167: 19.77
+	Hs
		439914 LCK_HUMAN (1-124): 9.23e-41: 143: 20.77		CD48_HUMAN (47-259): 1.51e-42: 149: 20.93
+	Hs
		557335 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		CEA21_HUMAN (9-284): 5.04e-35: 131: 16.08
+	Hs
		557081 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		CD33_HUMAN (40-276): 3.3e-24: 103: 16.73
+	Hs
		463499 LYN_HUMAN (1-124): 5.81e-39: 138: 19.23		PTK7_HUMAN (48-318): 4.65e-21: 96.5: 7.04
+	Hs
		439900 LCK_HUMAN (1-124): 9.23e-41: 143: 20.77		CD2_HUMAN (10-323): 5.87e-18: 85.4: 18.83
+	Hs
		440293 FYN_HUMAN (1-124): 8.26e-37: 132: 18.66		CD2_HUMAN (10-323): 5.87e-18: 85.4: 18.83
+	Hs
		463053 YES_HUMAN (1-124): 7.76e-39: 138: 20.61		CXAR_HUMAN (7-300): 1.22e-15: 78.8: 14.05
+	Hs
		463448 LYN_HUMAN (1-124): 5.81e-39: 138: 19.23		CXAR_HUMAN (7-300): 1.22e-15: 78.8: 14.05
+	Hs
		463875 LYN_HUMAN (1-124): 5.81e-39: 138: 19.23		ROBO1_HUMAN (23-177): 5.17e-13: 72.2: 10.35
+	Hs
		557323 SRC_HUMAN (1-124): 9.34e-37: 132: 22.90		MYLK_HUMAN (141-230): 2.68e-11: 66.8: 16.50