HitPredict

Interactor 1: DHX9 (Q08211)
ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A)
Gene: DHX9

Interactor 2: DICER (Q9UPY3)
Endoribonuclease Dicer (EC 3.1.26.3) (Helicase with RNase motif) (Helicase MOI)
Gene: DICER1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.839

The method score is based on:

Property Details
Experiments 35271311, 17531811, 21858095
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Dicer_dimer, DEAD~Helicase_C, DEAD~Ribonuclease_3, Dicer_dsRBD~dsrm, Dicer_platform~dsrm, Helicase_C~dsrm, PAZ~dsrm, Ribonuclease_3~dsrm, HA2_C~Helicase_C, DEAD~HA2_N, HA2_N~Helicase_C, Dicer_dsRBD~Helicase_C, Dicer_PBD~Helicase_C, Helicase_C~Helicase_C, Helicase_C~Ribonuclease_3, Helicase_C~OB_NTP_bind
Common GO terms GO:0003723 - RNA binding
GO:0003725 - double-stranded RNA binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1270
Hs

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Last updated: 11Aug2025