HitPredict

Interactor 1: M9NCY1 (M9NCY1)
Lim3, isoform E
Gene: Lim3

Interactor 2: Q9VJ37 (Q9VJ37)
Tailup, isoform A (Tailup, isoform C)
Gene: tup

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30995488, 14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain, LIM~LIM
Common GO terms	GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus GO:0008045 - motor neuron axon guidance
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 405 Dm			1 534
+	Dm
		114751 M9PD53_DROME (2-405): 2.72e-88: 279: 100.00		P92031_DROME (1-534): 3.63e-102: 319: 99.63
+	Dm
		1368258 Q9VJ00_DROME (2-405): 6.17e-88: 277: 100.00		Q9VJ37_DROME (1-534): 2.34e-102: 320: 100.00
+	Hs
		822689 LHX3_HUMAN (3-356): 7.53e-73: 234: 48.26		LHX1_HUMAN (53-452): 2.37e-57: 198: 24.34
+	Dm
		1368263 Q9VJ00_DROME (2-405): 6.17e-88: 277: 100.00		Q9VVB5_DROME (9-284): 6.09e-32: 131: 14.24
+	Hs
		1251418 LHX4_HUMAN (1-361): 9.05e-75: 239: 47.91		LMO3_HUMAN (44-183): 3.97e-42: 149: 32.17
+	Hs
		1251463 LHX5_HUMAN (7-369): 2.07e-61: 205: 31.62		LMO3_HUMAN (44-183): 3.97e-42: 149: 32.17
+	Hs
		903763 LHX4_HUMAN (1-361): 9.05e-75: 239: 47.91		LMO4_HUMAN (54-170): 9.38e-27: 108: 42.50
+	Hs
		1255791 LHX3_HUMAN (3-356): 7.53e-73: 234: 48.26		LMX1A_HUMAN (6-111): 1.01e-20: 95.9: 17.27
+	Mm
		864805 LHX4_MOUSE (1-361): 4.51e-75: 240: 48.17		ISL2_MOUSE (15-112): 3.81e-16: 82.1: 17.48
+	Hs
		1281161 LHX4_HUMAN (1-361): 9.05e-75: 239: 47.91		ISL2_HUMAN (15-112): 2e-16: 82.9: 17.48
+	Hs
		899929 LHX4_HUMAN (1-361): 9.05e-75: 239: 47.91		ISL1_HUMAN (5-108): 4.31e-16: 81.7: 14.41
+	Hs
		1281195 LHX4_HUMAN (1-361): 9.05e-75: 239: 47.91		LHX3_HUMAN (10-109): 8.66e-15: 78.2: 20.19
+	Hs
		1283500 LHX3_HUMAN (3-356): 7.53e-73: 234: 48.26		ISL2_HUMAN (15-112): 2e-16: 82.9: 17.48
+	Hs
		899935 LHX3_HUMAN (3-356): 7.53e-73: 234: 48.26		ISL1_HUMAN (5-108): 4.31e-16: 81.7: 14.41
+	Mm
		839895 LHX3_MOUSE (3-356): 5.25e-70: 227: 48.79		ISL1_MOUSE (5-108): 4.31e-16: 81.7: 14.41
+	Hs
		1255789 LMX1A_HUMAN (1-327): 2.63e-61: 204: 27.68		LMX1A_HUMAN (6-111): 1.01e-20: 95.9: 17.27
+	Hs
		899927 LMX1A_HUMAN (1-327): 2.63e-61: 204: 27.68		ISL1_HUMAN (5-108): 4.31e-16: 81.7: 14.41
+	Hs
		822660 LHX1_HUMAN (7-365): 2.93e-59: 199: 30.96		ISL2_HUMAN (15-112): 2e-16: 82.9: 17.48