HitPredict

Interactor 1: AMER1 (Q5JTC6)
APC membrane recruitment protein 1 (Amer1) (Protein FAM123B) (Wilms tumor gene on the X chromosome protein)
Gene: AMER1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	25332235, 25900982, 28514442, 33961781, 17510365
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0008013 - beta-catenin binding GO:0016055 - Wnt signaling pathway GO:0060828 - regulation of canonical Wnt signaling pathway
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 1135 Hs			1 605
+	Hs
		1127785 AMER1_HUMAN (1-1135): 0: 1738: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69