HitPredict

Interactor 1: BDF1 (P35817)
Bromodomain-containing factor 1
Gene: BDF1

Interactor 2: SPP1 (Q03012)
COMPASS component SPP1 (Complex proteins associated with SET1 protein SPP1) (Set1C component SPP1) (Suppressor of PRP protein 1)
Gene: SPP1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	22875988
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Bromodomain~PHD
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 686 Sc			1 353
+	Sc
		777045 BDF1_YEAST (1-671): 1.97e-150: 454: 100.00		YNG2_YEAST (12-74): 7.22e-11: 64: 33.33
+	Hs
		639850 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		PHF8_HUMAN (22-205): 5.53e-40: 152: 21.39
+	Hs
		1446440 BRD7_HUMAN (14-550): 3.84e-60: 215: 13.60		PHF8_HUMAN (22-205): 5.53e-40: 152: 21.39
+	Sc
		781785 RSC4_YEAST (105-686): 7.61e-56: 203: 15.22		SET3_YEAST (4-140): 2.88e-27: 114: 19.05
+	Hs
		1461510 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		PHF8_HUMAN (22-205): 5.53e-40: 152: 21.39
+	Hs
		639754 TAF1_HUMAN (103-613): 1.39e-58: 216: 12.38		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		1141365 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		PHF8_HUMAN (22-205): 5.53e-40: 152: 21.39
+	Hs
		1368522 CBP_HUMAN (249-418): 1.17e-36: 150: 25.73		ING1_HUMAN (9-95): 7.08e-22: 97.6: 28.89
+	Hs
		272796 BRD2_HUMAN (297-569): 2.1e-27: 120: 17.83		PHF2_HUMAN (22-203): 1.93e-31: 127: 19.29
+	Hs
		272827 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		PHF2_HUMAN (22-203): 1.93e-31: 127: 19.29
+	Hs
		342370 BRD1_HUMAN (40-340): 4.53e-37: 151: 13.78		ING4_HUMAN (9-76): 3.77e-19: 87.5: 32.39
+	Hs
		1452098 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		ING3_HUMAN (10-79): 1.14e-18: 88.3: 35.62
+	Hs
		1461509 BRPF3_HUMAN (62-286): 3.09e-34: 142: 15.56		ING4_HUMAN (9-76): 3.77e-19: 87.5: 32.39
+	Hs
		674149 BRD2_HUMAN (297-569): 2.1e-27: 120: 17.83		BPTF_HUMAN (11-126): 5.28e-22: 99.9: 22.22
+	Hs
		1086767 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		BPTF_HUMAN (11-126): 5.28e-22: 99.9: 22.22
+	Hs
		259864 BRD4_HUMAN (267-427): 2.87e-26: 117: 26.71		BPTF_HUMAN (11-126): 5.28e-22: 99.9: 22.22
+	Hs
		1218888 PHIP_HUMAN (108-640): 1.65e-30: 130: 12.78		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		1141363 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		ING4_HUMAN (9-76): 3.77e-19: 87.5: 32.39
+	Hs
		674199 BRD2_HUMAN (297-569): 2.1e-27: 120: 17.83		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86
+	Hs
		1141166 BRD3_HUMAN (306-466): 5.54e-27: 119: 23.60		TAF3_HUMAN (27-69): 1.38e-14: 77.1: 41.86