HitPredict

Interactor 1: CP135 (Q66GS9)
Centrosomal protein of 135 kDa (Cep135) (Centrosomal protein 4)
Gene: CEP135

Interactor 2: RB6I2 (Q8IUD2)
ELKS/Rab6-interacting/CAST family member 1 (ERC-1) (Rab6-interacting protein 2)
Gene: ERC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26638075, 26496610
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 1140 Hs			1 1116
+	Hs
		1067444 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		RB6I2_HUMAN (1-1116): 2.23e-82: 293: 100.00
+	Hs
		725179 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		1012560 CP135_HUMAN (1-1140): 1.31e-85: 303: 100.00		CGNL1_HUMAN (404-989): 2.32e-10: 67.4: 20.85
+	Hs
		724687 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH9_HUMAN (2-736): 1.6e-33: 142: 9.92
+	Hs
		528435 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH4_HUMAN (418-1116): 7.23e-33: 141: 13.92
+	Dd
		445145 MYS2_DICDI (1-1088): 1.21e-53: 208: 12.19		MYS2_DICDI (3-471): 6.77e-17: 88.6: 8.26
+	Hs
		528432 MYH8_HUMAN (417-1140): 2.53e-39: 162: 14.25		MYH13_HUMAN (1-745): 5.53e-31: 134: 9.88
+	Hs
		502933 MYH3_HUMAN (474-1140): 7.75e-35: 147: 14.20		MYH4_HUMAN (418-1116): 7.23e-33: 141: 13.92
+	Hs
		1067423 EEA1_HUMAN (1-997): 1.2e-47: 188: 12.43		EEA1_HUMAN (557-1116): 4.52e-19: 95.6: 12.23
+	Hs
		148466 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		725097 MYH11_HUMAN (417-1140): 5.39e-44: 177: 15.36		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Rn
		361106 MYH6_RAT (474-1128): 1.63e-33: 143: 14.31		MYH6_RAT (3-698): 6.68e-29: 127: 10.00
+	Hs
		528356 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH6_HUMAN (3-544): 6.64e-24: 111: 9.47
+	Hs
		148461 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		CTRO_HUMAN (156-792): 2.47e-18: 93.5: 12.63
+	Hs
		725095 MYH10_HUMAN (410-1140): 1.54e-40: 166: 13.95		MYH10_HUMAN (664-1113): 2.61e-18: 93.3: 12.09
+	Hs
		502901 MYH6_HUMAN (382-1137): 2.97e-37: 155: 12.55		MYH3_HUMAN (4-532): 1.56e-20: 100: 10.40
+	Ce
		218984 Q21000_CAEEL (497-1139): 1.72e-35: 149: 11.38		O44490_CAEEL (161-834): 3.6e-09: 63.2: 20.15