HitPredict

Interactor 1: TRAF7 (Q6Q0C0)
E3 ubiquitin-protein ligase TRAF7 (EC 2.3.2.-) (EC 2.3.2.27) (RING finger and WD repeat-containing protein 1) (RING finger protein 119) (RING-type E3 ubiquitin transferase TRAF7) (TNF receptor-associated factor 7)
Gene: TRAF7

Interactor 2: LCA5 (Q86VQ0)
Lebercilin (Leber congenital amaurosis 5 protein)
Gene: LCA5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	26638075, unassigned1272
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 670 Hs			1 697
+	Hs
		148858 TAF5_HUMAN (98-669): 5.6e-83: 280: 14.17		CTRO_HUMAN (46-497): 3.91e-10: 65.4: 12.14
+	Hs
		551870 FBW1A_HUMAN (175-586): 2.32e-60: 214: 15.99		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		1189782 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		MYH14_HUMAN (48-530): 2.28e-23: 108: 14.09
+	Hs
		1281519 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		MRCKB_HUMAN (159-608): 4.91e-16: 84.7: 13.39
+	Hs
		551854 NLE1_HUMAN (119-503): 2.65e-45: 170: 13.81		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		724952 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		MYH9_HUMAN (217-636): 2.15e-09: 63.1: 9.91
+	Hs
		725215 FBXW7_HUMAN (70-499): 3.77e-45: 173: 12.60		MYH10_HUMAN (231-628): 2.38e-09: 63.1: 6.48
+	Hs
		1288351 SNR40_HUMAN (177-463): 1.23e-22: 102: 13.04		ITSN2_HUMAN (101-588): 9.72e-28: 122: 13.77
+	Hs
		903334 WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21		MYH14_HUMAN (48-530): 2.28e-23: 108: 14.09
+	Hs
		551632 LIS1_HUMAN (140-426): 1.68e-23: 105: 10.82		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		551766 WDR5B_HUMAN (100-464): 4.85e-24: 105: 11.73		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		551655 WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21		DESP_HUMAN (31-635): 8.92e-16: 83.9: 12.21
+	Hs
		61736 SNR40_HUMAN (177-463): 1.23e-22: 102: 13.04		A6H8W8_HUMAN (204-593): 2.93e-10: 65.8: 12.53
+	Hs
		149156 SNR40_HUMAN (177-463): 1.23e-22: 102: 13.04		CTRO_HUMAN (46-497): 3.91e-10: 65.4: 12.14
+	Hs
		148610 WDR5_HUMAN (99-424): 5.66e-20: 93.7: 10.21		CTRO_HUMAN (46-497): 3.91e-10: 65.4: 12.14