HitPredict

Interactor 1: NEB2 (Q6R891)
Neurabin-2 (Neurabin-II) (Protein phosphatase 1 regulatory subunit 9B) (Spinophilin)
Gene: Ppp1r9b

Interactor 2: DCLK1 (Q9JLM8)
Serine/threonine-protein kinase DCLK1 (EC 2.7.11.1) (Doublecortin-like and CAM kinase-like 1) (Doublecortin-like kinase 1)
Gene: DCLK1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30562941, 36417873
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004672 - protein kinase activity GO:0014069 - postsynaptic density GO:0030426 - growth cone
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Mm			1 756
+	Hs
		166604 NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84		DCLK1_HUMAN (1-756): 0: 867: 96.43
+	Hs
		166629 NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50		DCLK1_HUMAN (1-756): 0: 867: 96.43
+	Hs
		1234196 NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84		DCLK2_HUMAN (1-746): 0: 781: 63.43
+	Hs
		1234199 NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50		DCLK2_HUMAN (1-746): 0: 781: 63.43
+	Mm
		292337 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		DCX_MOUSE (6-346): 1.22e-142: 424: 72.21
+	Hs
		208290 NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84		DCX_HUMAN (6-344): 2.3e-142: 424: 72.62
+	Mm
		1161534 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KCC2D_MOUSE (401-741): 1.44e-131: 401: 34.49
+	Rn
		192513 NEB2_RAT (1-817): 2.42e-118: 379: 98.90		KCC2D_RAT (401-744): 8.35e-126: 387: 34.20
+	Rn
		192510 NEB2_RAT (1-817): 2.42e-118: 379: 98.90		KCC2A_RAT (402-727): 2.32e-125: 384: 37.46
+	Mm
		515240 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KCC2A_MOUSE (402-727): 2.32e-125: 384: 37.46
+	Hs
		1071685 NEB2_HUMAN (1-817): 5.5e-113: 365: 95.84		KS6A2_HUMAN (397-734): 5.49e-113: 360: 25.14
+	Hs
		1073494 NEB1_HUMAN (1-817): 1.2e-100: 338: 46.50		KS6A1_HUMAN (355-736): 1.13e-110: 354: 21.66
+	Rn
		192511 NEB2_RAT (1-817): 2.42e-118: 379: 98.90		KCC2G_RAT (403-663): 7.52e-66: 229: 44.15
+	Mm
		1164026 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KCC2G_MOUSE (403-663): 2.12e-65: 228: 44.15
+	Rn
		192509 NEB2_RAT (1-817): 2.42e-118: 379: 98.90		KCC2B_RAT (403-663): 1.44e-63: 223: 44.15
+	Mm
		659460 NEB2_MOUSE (1-817): 1.3e-116: 374: 100.00		KCC2B_MOUSE (403-663): 1.39e-63: 223: 44.15
+	Rn
		506740 DLG1_RAT (244-705): 1.52e-41: 165: 16.22		KCC2A_RAT (402-727): 2.32e-125: 384: 37.46
+	Hs
		1271040 DLG3_HUMAN (269-734): 1.64e-40: 162: 16.36		KCC2A_HUMAN (402-741): 2.09e-125: 384: 37.10
+	Rn
		506744 DLG3_RAT (224-734): 2.62e-39: 158: 16.04		KCC2A_RAT (402-727): 2.32e-125: 384: 37.46
+	Hs
		1073454 PAR3L_HUMAN (159-758): 1.59e-43: 172: 15.59		KS6A1_HUMAN (355-736): 1.13e-110: 354: 21.66