Interactor 1: DLDH (O08749)
Dihydrolipoyl dehydrogenase, mitochondrial (EC 1.8.1.4) (Dihydrolipoamide dehydrogenase)
Gene: Dld

Interactor 2: ODP2 (Q8BMF4)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2)
Gene: Dlat

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29222160
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains E3_binding~Pyr_redox_2, E3_binding~Pyr_redox_dim
Common GO terms GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006086 - pyruvate decarboxylation to acetyl-CoA
GO:0043209 - myelin sheath
GO:0045254 - pyruvate dehydrogenase complex
and 1 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 509
Mm

1 642
+ Hs
+ At
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Sc
+ Sc
+ Gs
+ Ec
+ At
+ Ec
+ Ss

Service provided by Combinatics, Japan

Last updated: 11Aug2025