HitPredict

Interactor 1: MILK1 (Q8N3F8)
MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Gene: MICALL1

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005770 - late endosome GO:0031941 - filamentous actin GO:0045296 - cadherin binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 863 Hs			1 639
+	Hs
		1232325 MILK1_HUMAN (1-863): 1.02e-88: 302: 100.00		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		1186102 MICA3_HUMAN (8-107): 1.44e-22: 106: 54.00		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		521521 ACTN1_HUMAN (3-227): 1.28e-64: 235: 29.78		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		211557 ACTN4_HUMAN (3-227): 5.94e-64: 233: 29.78		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		209124 MICA1_HUMAN (377-811): 1.09e-42: 170: 18.40		NCK2_HUMAN (2-361): 2.2e-59: 205: 16.17
+	Hs
		924482 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		298946 ACTN1_HUMAN (3-227): 1.28e-64: 235: 29.78		SRBS2_HUMAN (6-215): 1e-18: 92.7: 18.40
+	Hs
		211443 ACTN4_HUMAN (3-227): 5.94e-64: 233: 29.78		SRBS2_HUMAN (6-215): 1e-18: 92.7: 18.40
+	Hs
		924720 MICA1_HUMAN (377-811): 1.09e-42: 170: 18.40		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Mm
		1113251 ACTN1_MOUSE (3-227): 4.82e-64: 233: 29.33		SRBS2_MOUSE (258-329): 5.28e-09: 61.5: 20.83
+	Hs
		963335 SPTB2_HUMAN (3-246): 8.29e-57: 215: 28.69		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64
+	Hs
		235555 MICA1_HUMAN (377-811): 1.09e-42: 170: 18.40		VINEX_HUMAN (163-343): 4.52e-13: 74.2: 18.28