HitPredict

Interactor 1: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Interactor 2: KDIS (Q9ULH0)
Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein)
Gene: KIDINS220

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 975 Hs			1 1771
+	Hs
		862733 UTRN_HUMAN (4-702): 2.48e-11: 70.4: 12.03		KDIS_HUMAN (13-1771): 0: 2597: 100.00
+	Mm
		597663 SPTN1_MOUSE (7-457): 2.42e-09: 63.7: 10.44		ANK2_MOUSE (1-465): 1.02e-121: 429: 24.95
+	Hs
		1252117 SYNE3_HUMAN (1-975): 2.45e-68: 248: 100.00		ANKH1_HUMAN (359-505): 4.26e-23: 110: 12.16
+	Hs
		772749 MYH9_HUMAN (2-691): 1.9e-22: 106: 9.68		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		1030639 SPTN1_HUMAN (181-883): 5.88e-22: 105: 13.75		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		1091395 SPTN1_HUMAN (181-883): 5.88e-22: 105: 13.75		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Mm
		109265 SPTB2_MOUSE (5-704): 2.11e-20: 100: 12.94		ANK3_MOUSE (240-506): 5.54e-63: 240: 22.18
+	Hs
		1091457 SPTN4_HUMAN (6-825): 3.78e-18: 92.7: 13.61		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		1028731 SPTB2_HUMAN (7-847): 9.1e-17: 87.9: 15.19		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		1028748 SPTB2_HUMAN (7-847): 9.1e-17: 87.9: 15.19		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		1030712 MACF1_HUMAN (9-917): 2.94e-14: 79.9: 12.37		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		174745 SPTN2_HUMAN (5-282): 6.11e-12: 72.3: 13.31		ANK2_HUMAN (234-506): 1.27e-62: 240: 18.89
+	Hs
		174752 SPTN2_HUMAN (5-282): 6.11e-12: 72.3: 13.31		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Hs
		862639 UTRN_HUMAN (4-702): 2.48e-11: 70.4: 12.03		ANK3_HUMAN (240-506): 3.83e-62: 238: 21.84
+	Mm
		86327 B9EKJ1_MOUSE (7-457): 2.42e-09: 63.7: 10.44		ANK3_MOUSE (240-506): 5.54e-63: 240: 22.18
+	Hs
		386434 SPTA1_HUMAN (5-651): 8.88e-17: 88.1: 11.36		ANK1_HUMAN (271-530): 2.48e-47: 189: 19.08
+	Hs
		592928 SPTB2_HUMAN (7-847): 9.1e-17: 87.9: 15.19		ANK1_HUMAN (271-530): 2.48e-47: 189: 19.08
+	Hs
		920439 SPTN1_HUMAN (181-883): 5.88e-22: 105: 13.75		DAPK1_HUMAN (4-305): 4.94e-35: 149: 31.58
+	Hs
		920429 SPTB2_HUMAN (7-847): 9.1e-17: 87.9: 15.19		DAPK1_HUMAN (4-305): 4.94e-35: 149: 31.58
+	Hs
		174726 SPTN2_HUMAN (5-282): 6.11e-12: 72.3: 13.31		DAPK1_HUMAN (4-305): 4.94e-35: 149: 31.58