Interactor 1: NAL10 (Q86W26)
NACHT, LRR and PYD domains-containing protein 10 (Nucleotide-binding oligomerization domain protein 8)
Gene: NLRP10
Interactor 2: ASC (Q9ULZ3)
Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1)
Gene: PYCARD
Species: Homo sapiens
Source: innatedb
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 15096476 |
| Identification Methods | anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PYRIN~PYRIN |
| Common GO terms | GO:0002218 - activation of innate immune response GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006954 - inflammatory response and 5 others more... |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025