HitPredict

Interactor 1: FRAS1 (Q86XX4)
Extracellular matrix organizing protein FRAS1 (Fraser syndrome 1 protein)
Gene: FRAS1

Interactor 2: EGFL7 (Q9UHF1)
Epidermal growth factor-like protein 7 (EGF-like protein 7) (Multiple epidermal growth factor-like domains protein 7) (Multiple EGF-like domains protein 7) (NOTCH4-like protein) (Vascular endothelial statin) (VE-statin) (Zneu1)
Gene: EGFL7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 4008 Hs			1 273
+	Dm
		753707 DS_DROME (1236-2779): 1.13e-171: 601: 9.12		FAT_DROME (140-272): 7.69e-13: 70.6: 11.80
+	Hs
		1459916 NOTC3_HUMAN (355-1145): 4.51e-55: 217: 12.17		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1047772 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Hs
		1126051 PCDBG_HUMAN (2982-3483): 2.67e-67: 247: 9.47		GAS6_HUMAN (54-186): 1.55e-19: 89.8: 25.18
+	Hs
		317563 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		SLIT2_HUMAN (59-271): 1.73e-25: 107: 12.29
+	Mm
		204911 NOTC2_MOUSE (5-719): 2.57e-40: 168: 11.30		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Mm
		1223430 NOTC3_MOUSE (4-629): 5.5e-36: 154: 13.87		EGFL7_MOUSE (1-272): 1.08e-38: 138: 78.10
+	Hs
		452091 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		PROS_HUMAN (24-201): 7.76e-19: 87.9: 19.37
+	Hs
		1008030 NOTC3_HUMAN (355-1145): 4.51e-55: 217: 12.17		JAG1_HUMAN (66-168): 2.85e-10: 62.4: 28.57
+	Hs
		857591 NOTC3_HUMAN (355-1145): 4.51e-55: 217: 12.17		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		1047591 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		NPNT_HUMAN (80-173): 3.93e-11: 64.8: 32.35
+	Hs
		1008015 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		JAG1_HUMAN (66-168): 2.85e-10: 62.4: 28.57
+	Hs
		857423 NOTC2_HUMAN (345-1137): 3.79e-51: 204: 12.46		NOTC1_HUMAN (85-183): 3.37e-09: 59.4: 21.57
+	Hs
		1453625 CRIM1_HUMAN (473-1103): 2.28e-14: 82.2: 13.84		EGFL7_HUMAN (1-273): 3.18e-41: 144: 100.00
+	Rn
		1032132 NAC1_RAT (2771-3010): 3.26e-34: 147: 22.69		FBLN5_RAT (70-176): 7.77e-16: 78.6: 30.17
+	Hs
		1126058 PCDB5_HUMAN (3075-3493): 1.58e-30: 134: 11.68		GAS6_HUMAN (54-186): 1.55e-19: 89.8: 25.18
+	Dm
		262737 FUR2_DROME (17-477): 8.32e-19: 97.2: 16.30		TENM_DROME (64-272): 2.73e-27: 112: 16.36
+	Dm
		95089 NOTCH_DROME (4-559): 4.21e-23: 111: 13.03		E1JHA6_DROME (2-138): 3.41e-13: 71.4: 12.93
+	Dm
		451712 NOTCH_DROME (4-559): 4.21e-23: 111: 13.03		NOTCH_DROME (68-172): 2.45e-09: 59.8: 22.32
+	Dm
		451716 NOTCH_DROME (4-559): 4.21e-23: 111: 13.03		DL_DROME (53-168): 3.56e-09: 59: 25.58