HitPredict

Interactor 1: PSDE (O00487)
26S proteasome non-ATPase regulatory subunit 14 (EC 3.4.19.-) (26S proteasome regulatory subunit RPN11) (26S proteasome-associated PAD1 homolog 1)
Gene: PSMD14

Interactor 2: UBC (P0CG48)
Polyubiquitin-C [Cleaved into: Ubiquitin]
Gene: UBC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	1.00	0.956

Property	Details
Experiments	27428775, 30745168, 35530310, 28190767, 34642328, 36114200, 16196087
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	JAB~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 310 Hs			1 685
+	Hs
		476142 CSN5_HUMAN (1-305): 6.24e-83: 255: 28.35		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		176926 EIF3H_HUMAN (23-298): 5.55e-55: 183: 21.05		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		317703 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		UBC_HUMAN (1-685): 0: 846: 100.00
+	Hs
		476192 STALP_HUMAN (18-208): 4.08e-42: 152: 18.65		UBC_HUMAN (1-685): 0: 846: 100.00
+	Sc
		477336 RPN11_YEAST (1-310): 1.59e-93: 281: 64.84		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	At
		1092172 PSDE_ARATH (1-309): 1.07e-109: 322: 79.61		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Sc
		477501 CSN5_YEAST (14-282): 4.39e-45: 160: 24.11		UBI4P_YEAST (381-685): 5e-122: 370: 95.74
+	At
		1091793 CSN5A_ARATH (2-303): 1.72e-80: 249: 29.78		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		1091965 EIF3H_ARATH (7-304): 4.37e-72: 227: 18.61		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		130837 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		RS27A_HUMAN (609-684): 7.23e-41: 148: 100.00
+	Mm
		192886 PSDE_MOUSE (1-310): 1.28e-110: 324: 100.00		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	At
		1091969 PSD7B_ARATH (15-256): 1.76e-49: 168: 18.43		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	At
		188941 PSD7A_ARATH (15-256): 5.45e-49: 167: 18.04		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		130693 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		ISG15_HUMAN (228-380): 1.72e-28: 113: 32.69
+	At
		1091838 AMSH1_ARATH (30-213): 1.94e-45: 162: 17.39		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Hs
		130704 PSDE_HUMAN (1-310): 1.28e-110: 324: 100.00		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	At
		137953 EIF3F_ARATH (17-277): 2.76e-46: 159: 19.39		UBQ3_ARATH (457-685): 3.23e-85: 272: 95.63
+	Mm
		193512 CSN5_MOUSE (1-305): 4.65e-83: 255: 28.35		UBC_MOUSE (1-108): 9.43e-30: 127: 90.74
+	Hs
		317702 STABP_HUMAN (17-199): 5.28e-44: 157: 17.84		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70
+	Hs
		474952 BRCC3_HUMAN (32-188): 1e-41: 148: 25.79		UBB_HUMAN (1-77): 7.83e-26: 108: 98.70