HitPredict

Interactor 1: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Interactor 2: DUS19 (Q8WTR2)
Dual specificity protein phosphatase 19 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity phosphatase TS-DSP1) (Low molecular weight dual specificity phosphatase 3) (LMW-DSP3) (Protein phosphatase SKRP1) (Stress-activated protein kinase pathway-regulating phosphatase 1) (SAPK pathway-regulating phosphatase 1)
Gene: DUSP19

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1503 Hs			1 217
+	Hs
		326734 LMTK2_HUMAN (1-1503): 0: 1229: 100.00		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		1163848 LMTK2_HUMAN (1-1503): 0: 1229: 100.00		DUS6_HUMAN (47-214): 8.81e-60: 193: 33.33
+	Hs
		1310860 LMTK2_HUMAN (1-1503): 0: 1229: 100.00		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		1229392 LMTK2_HUMAN (1-1503): 0: 1229: 100.00		DUS29_HUMAN (64-204): 1.58e-53: 172: 30.20
+	Hs
		703950 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS1_HUMAN (18-217): 1.24e-74: 231: 29.85
+	Hs
		1161866 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS5_HUMAN (18-217): 8.77e-66: 209: 27.54
+	Hs
		1251949 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS9_HUMAN (38-216): 1.41e-65: 208: 31.38
+	Hs
		326725 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		1163843 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS6_HUMAN (47-214): 8.81e-60: 193: 33.33
+	Hs
		1251932 LMTK1_HUMAN (14-1500): 0: 707: 29.02		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		1229391 LMTK1_HUMAN (14-1500): 0: 707: 29.02		DUS29_HUMAN (64-204): 1.58e-53: 172: 30.20
+	Hs
		1145755 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS19_HUMAN (1-217): 9.39e-89: 262: 100.00
+	Hs
		326705 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		1145739 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS6_HUMAN (47-214): 8.81e-60: 193: 33.33
+	Hs
		1145774 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS16_HUMAN (42-207): 2.63e-57: 193: 28.14
+	Hs
		1145753 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS18_HUMAN (49-216): 1.32e-60: 189: 27.98
+	Hs
		1145779 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		DUS21_HUMAN (58-216): 8.91e-59: 185: 29.56
+	Hs
		1145756 ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30		STYX_HUMAN (42-215): 5.88e-57: 181: 29.83
+	Hs
		326658 FGFR2_HUMAN (33-454): 3.18e-122: 404: 20.52		DUS14_HUMAN (62-216): 2.73e-65: 202: 30.32
+	Hs
		464047 RET_HUMAN (5-489): 2e-119: 404: 18.93		DUS26_HUMAN (63-205): 2e-55: 177: 30.20