HitPredict

Interactor 1: NOP56 (O00567)
Nucleolar protein 56 (Nucleolar protein 5A)
Gene: NOP56

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	26496610, 34079125
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0016020 - membrane
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 594 Hs			1 670
+	Hs
		133468 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Hs
		133576 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX55_HUMAN (176-668): 5.77e-136: 413: 34.05
+	Sc
		593730 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		DBP4_YEAST (141-662): 8.19e-161: 483: 35.85
+	Dm
		1280026 Q95WY3_DROME (1-471): 0: 581: 61.67		DDX18_DROME (3-665): 2.33e-136: 417: 57.61
+	Sc
		593732 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		DBP4_YEAST (141-662): 8.19e-161: 483: 35.85
+	Sc
		976894 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Hs
		133679 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Dm
		1363481 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		DDX18_DROME (3-665): 2.33e-136: 417: 57.61
+	Sc
		976896 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Hs
		133615 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Hs
		133756 NOP56_HUMAN (1-594): 0: 661: 100.00		DDX49_HUMAN (195-565): 1.87e-54: 195: 33.95
+	Sc
		638905 NOP56_YEAST (5-438): 1.95e-180: 521: 53.62		SPB4_YEAST (197-618): 1.28e-57: 207: 32.29
+	Dm
		1367913 Q9VM69_DROME (4-491): 4.2e-166: 484: 36.89		DDX47_DROME (186-528): 6.51e-63: 219: 39.02
+	Sc
		638907 NOP58_YEAST (3-443): 3.77e-156: 459: 40.36		SPB4_YEAST (197-618): 1.28e-57: 207: 32.29