HitPredict

Interactor 1: THG1 (Q9NWX6)
Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase)
Gene: THG1L

Interactor 2: THG1 (Q9NWX6)
Probable tRNA(His) guanylyltransferase (EC 2.7.7.79) (Induced in high glucose-1) (IHG-1) (Interphase cytoplasmic foci protein 45) (tRNA-histidine guanylyltransferase)
Gene: THG1L

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.75 1.00 0.870

The method score is based on:

Property Details
Experiments 25416956, 21516116, 21059936
Identification Methods two hybrid, two hybrid array, molecular sieving, x-ray crystallography
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Thg1~Thg1, Thg1~Thg1C, Thg1C~Thg1C
Common GO terms GO:0000049 - tRNA binding
GO:0000287 - magnesium ion binding
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005524 - ATP binding
GO:0005525 - GTP binding
and 12 others

more...
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 298
Hs

1 298
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024