HitPredict

Interactor 1: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Interactor 2: VP37B (Q9H9H4)
Vacuolar protein sorting-associated protein 37B (hVps37B) (ESCRT-I complex subunit VPS37B)
Gene: VPS37B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	19531213, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 665 Hs			1 285
+	Hs
		1356973 SH3K1_HUMAN (1-665): 1.57e-126: 391: 100.00		PDC6I_HUMAN (18-282): 1.29e-46: 168: 16.51
+	Hs
		1437095 CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36		VP37B_HUMAN (1-285): 2.79e-70: 220: 100.00
+	Hs
		1357030 CD2AP_HUMAN (1-664): 1.84e-95: 309: 32.36		PDC6I_HUMAN (18-282): 1.29e-46: 168: 16.51
+	Dm
		1445614 Q9NHP2_DROME (3-623): 2.06e-40: 160: 16.55		Q9VB05_DROME (14-282): 5.12e-61: 208: 18.18
+	Hs
		987950 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		VP37B_HUMAN (1-285): 2.79e-70: 220: 100.00
+	Hs
		63237 SH3R2_HUMAN (1-608): 8.76e-38: 152: 16.56		VP37C_HUMAN (9-282): 5.56e-47: 162: 35.59
+	Hs
		222209 NCK2_HUMAN (244-432): 3.03e-17: 86.2: 21.24		VP37B_HUMAN (1-285): 2.79e-70: 220: 100.00
+	Dm
		1061458 GRAP_DROME (2-157): 3.83e-32: 125: 18.01		Q9VN88_DROME (8-200): 8.45e-55: 178: 31.61
+	Hs
		987797 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		PDC6I_HUMAN (18-282): 1.29e-46: 168: 16.51
+	Hs
		250339 VINEX_HUMAN (67-445): 6.54e-15: 80.5: 19.82		VP37B_HUMAN (1-285): 2.79e-70: 220: 100.00
+	Hs
		63181 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		VP37C_HUMAN (9-282): 5.56e-47: 162: 35.59
+	Mm
		1221266 GRB2_MOUSE (2-158): 8.55e-35: 133: 20.37		PDC6I_MOUSE (15-279): 3.57e-37: 141: 14.76
+	Hs
		1154143 ITSN1_HUMAN (77-423): 3.02e-14: 78.9: 14.56		PDC6I_HUMAN (18-282): 1.29e-46: 168: 16.51
+	Hs
		1357015 ITSN2_HUMAN (214-418): 8.13e-14: 77.4: 15.61		PDC6I_HUMAN (18-282): 1.29e-46: 168: 16.51
+	Hs
		63156 VINEX_HUMAN (67-445): 6.54e-15: 80.5: 19.82		VP37C_HUMAN (9-282): 5.56e-47: 162: 35.59
+	Hs
		63199 ARHG6_HUMAN (213-349): 2.26e-13: 75.5: 23.36		VP37C_HUMAN (9-282): 5.56e-47: 162: 35.59
+	Hs
		63163 SRBS2_HUMAN (3-155): 4.67e-11: 68.2: 30.86		VP37C_HUMAN (9-282): 5.56e-47: 162: 35.59
+	Hs
		67103 GRB2_HUMAN (2-158): 8.55e-35: 133: 20.37		CP096_HUMAN (13-280): 5.34e-09: 58.8: 14.70
+	Ce
		711445 SEM5_CAEEL (4-70): 2.01e-20: 92.7: 35.82		ALXA_CAEEL (1-280): 8.1e-16: 79.2: 14.24
+	Ce
		759619 Q9U2T9_CAEEL (142-349): 1.51e-13: 76.5: 18.48		ALXA_CAEEL (1-280): 8.1e-16: 79.2: 14.24