Interactor 1: FOXP3 (Q99JB6)
Forkhead box protein P3 (Scurfin) [Cleaved into: Forkhead box protein P3, C-terminally processed; Forkhead box protein P3 41 kDa form]
Gene: FOXP3

Interactor 2: ELF4 (Q9Z2U4)
ETS-related transcription factor Elf-4 (E74-like factor 4) (Myeloid Elf-1-like factor)
Gene: ELF4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22922362
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ets~Forkhead
Common GO terms GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0032715 - negative regulation of interleukin-6 production
GO:0032720 - negative regulation of tumor necrosis factor production
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 429
Mm

1 655
+ Mm
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+ Dm
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+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025