HitPredict

Interactor 1: RGS18 (Q99PG4)
Regulator of G-protein signaling 18 (RGS18)
Gene: RGS18

Interactor 2: GNAI3 (Q9DC51)
Guanine nucleotide-binding protein G(i) subunit alpha-3 (G(i) alpha-3)
Gene: GNAI3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11342430
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	G-alpha~RGS
Common GO terms	GO:0005737 - cytoplasm GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 235 Mm			1 354
+	Hs
		989885 RGS18_HUMAN (1-235): 6.47e-91: 269: 83.83		GNAI1_HUMAN (1-354): 1.72e-178: 500: 93.79
+	Hs
		476047 RGS18_HUMAN (1-235): 6.47e-91: 269: 83.83		GNAI3_HUMAN (1-354): 4.92e-176: 494: 98.31
+	Hs
		418751 RGS18_HUMAN (1-235): 6.47e-91: 269: 83.83		GNAI2_HUMAN (1-354): 8.28e-174: 488: 85.35
+	Hs
		475924 RGS7_HUMAN (23-234): 3e-75: 237: 24.77		GNAI3_HUMAN (1-354): 4.92e-176: 494: 98.31
+	Hs
		475923 RGS3_HUMAN (30-211): 7.95e-70: 233: 41.76		GNAI3_HUMAN (1-354): 4.92e-176: 494: 98.31
+	Hs
		893531 RGS18_HUMAN (1-235): 6.47e-91: 269: 83.83		GNAQ_HUMAN (1-353): 1.4e-160: 455: 50.85
+	Mm
		636989 RGS18_MOUSE (1-235): 1.89e-90: 268: 100.00		GNAQ_MOUSE (1-353): 7.58e-161: 455: 50.85
+	Hs
		418623 RGS3_HUMAN (30-211): 7.95e-70: 233: 41.76		GNAI2_HUMAN (1-354): 8.28e-174: 488: 85.35
+	Hs
		475908 RGS2_HUMAN (4-206): 5.66e-71: 217: 43.35		GNAI3_HUMAN (1-354): 4.92e-176: 494: 98.31
+	Hs
		297293 RGS9_HUMAN (17-235): 1.45e-70: 229: 25.78		GNAO_HUMAN (1-354): 2.81e-170: 479: 71.27
+	Hs
		418624 RGS4_HUMAN (38-224): 7.44e-66: 204: 40.96		GNAI2_HUMAN (1-354): 8.28e-174: 488: 85.35
+	Hs
		890709 RGS7_HUMAN (23-234): 3e-75: 237: 24.77		GNAQ_HUMAN (1-353): 1.4e-160: 455: 50.85
+	Bt
		235272 RGS9_BOVIN (17-235): 8.2e-71: 225: 26.22		GNAT1_BOVIN (1-354): 1.45e-163: 462: 64.69
+	Hs
		482589 RGS4_HUMAN (38-224): 7.44e-66: 204: 40.96		GNAO_HUMAN (1-354): 2.81e-170: 479: 71.27
+	Hs
		618442 RGS7_HUMAN (23-234): 3e-75: 237: 24.77		GNAZ_HUMAN (1-353): 3.79e-155: 441: 66.95
+	Hs
		715999 RGS3_HUMAN (30-211): 7.95e-70: 233: 41.76		GNA11_HUMAN (1-353): 4.8e-156: 443: 50.00
+	Hs
		833397 RGS2_HUMAN (4-206): 5.66e-71: 217: 43.35		GNAQ_HUMAN (1-353): 1.4e-160: 455: 50.85
+	Hs
		890697 RGS4_HUMAN (38-224): 7.44e-66: 204: 40.96		GNAQ_HUMAN (1-353): 1.4e-160: 455: 50.85
+	Hs
		721445 RGS2_HUMAN (4-206): 5.66e-71: 217: 43.35		GNA15_HUMAN (4-353): 7.05e-143: 411: 42.54
+	Hs
		833403 RGS2_HUMAN (4-206): 5.66e-71: 217: 43.35		GNAS2_HUMAN (1-353): 3.1e-138: 400: 38.17