HitPredict

Interactor 1: AP3D1 (O14617)
AP-3 complex subunit delta-1 (AP-3 complex subunit delta) (Adaptor-related protein complex 3 subunit delta-1) (Delta-adaptin)
Gene: AP3D1

Interactor 2: AP3S1 (Q92572)
AP-3 complex subunit sigma-1 (AP-3 complex subunit sigma-3A) (Adaptor-related protein complex 3 subunit sigma-1) (Clathrin-associated/assembly/adaptor protein, small 3) (Sigma-3A-adaptin) (Sigma3A-adaptin) (Sigma-adaptin 3a)
Gene: AP3S1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 23144738, 15469849, 35235311, 37071682, 31839598, 28514442, 33961781, 39422127
Identification Methods affinity chromatography technology, two hybrid, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0008089 - anterograde axonal transport
and 10 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1153
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Service provided by Combinatics, Japan

Last updated: 11Aug2025