HitPredict

Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: LPAR1 (Q92633)
Lysophosphatidic acid receptor 1 (LPA receptor 1) (LPA-1) (Lysophosphatidic acid receptor Edg-2)
Gene: LPAR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1001 Hs			1 364
+	Hs
		328366 AT2A3_HUMAN (1-999): 0: 950: 75.88		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89
+	Hs
		561507 AT2A2_HUMAN (1-1000): 0: 950: 83.40		CNR2_HUMAN (46-349): 7.45e-71: 227: 24.52
+	Hs
		428908 AT2A2_HUMAN (1-1000): 0: 950: 83.40		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		561517 AT2A2_HUMAN (1-1000): 0: 950: 83.40		OPRD_HUMAN (1-354): 1.96e-63: 208: 17.39
+	Hs
		1274529 AT2A3_HUMAN (1-999): 0: 950: 75.88		LPAR2_HUMAN (23-364): 1.03e-59: 197: 53.06
+	Hs
		598761 AT2A3_HUMAN (1-999): 0: 950: 75.88		S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86
+	Hs
		328306 AT1A3_HUMAN (2-998): 0: 800: 26.20		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89
+	Hs
		392982 AT1A1_HUMAN (2-998): 0: 803: 26.10		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		530850 AT1A3_HUMAN (2-998): 0: 800: 26.20		GPR12_HUMAN (58-329): 3.92e-68: 219: 29.09
+	Hs
		530839 AT1A3_HUMAN (2-998): 0: 800: 26.20		NK3R_HUMAN (13-364): 1.05e-63: 211: 15.85
+	Hs
		530964 AT1A3_HUMAN (2-998): 0: 800: 26.20		NPFF1_HUMAN (11-363): 4.51e-62: 206: 19.47
+	Hs
		530844 AT1A3_HUMAN (2-998): 0: 800: 26.20		OPRX_HUMAN (2-343): 2.72e-60: 200: 16.67
+	Hs
		530828 AT1A3_HUMAN (2-998): 0: 800: 26.20		S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86
+	Hs
		328308 AT2B4_HUMAN (5-993): 0: 761: 25.05		S1PR4_HUMAN (1-360): 9.27e-72: 230: 30.89
+	Hs
		208456 AT2B3_HUMAN (3-993): 0: 767: 24.31		OX2R_HUMAN (10-359): 1.2e-66: 218: 16.29
+	Hs
		208448 AT2B4_HUMAN (5-993): 0: 761: 25.05		OX2R_HUMAN (10-359): 1.2e-66: 218: 16.29
+	Hs
		428921 AT2B4_HUMAN (5-993): 0: 761: 25.05		ADRB2_HUMAN (54-350): 1.7e-66: 217: 17.38
+	Hs
		619198 AT2B4_HUMAN (5-993): 0: 761: 25.05		NK3R_HUMAN (13-364): 1.05e-63: 211: 15.85
+	Hs
		781059 AT2B3_HUMAN (3-993): 0: 767: 24.31		OPRX_HUMAN (2-343): 2.72e-60: 200: 16.67
+	Hs
		598738 AT2B3_HUMAN (3-993): 0: 767: 24.31		S1PR1_HUMAN (10-333): 3.19e-59: 197: 36.86