HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35918322
Identification Methods	enzymatic study, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 136
+	Hs
		167572 IKKA_HUMAN (1-745): 0: 588: 100.00		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		254470 ROCK2_HUMAN (10-739): 5.13e-122: 399: 16.40		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	At
		886660 CDPKB_ARATH (5-439): 6.96e-123: 378: 19.27		H31_ARATH (1-136): 1.67e-60: 184: 97.06
+	At
		886659 CDPK4_ARATH (1-525): 3.76e-121: 374: 17.19		H31_ARATH (1-136): 1.67e-60: 184: 97.06
+	Hs
		270399 KS6A5_HUMAN (1-314): 1.41e-86: 292: 22.05		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		270424 KS6A5_HUMAN (1-314): 1.41e-86: 292: 22.05		H32_HUMAN (1-136): 6.5e-61: 185: 99.27
+	Hs
		610712 KAPCB_HUMAN (5-316): 3.65e-89: 285: 26.96		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		610715 KAPCB_HUMAN (5-316): 3.65e-89: 285: 26.96		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		610742 KAPCB_HUMAN (5-316): 3.65e-89: 285: 26.96		H32_HUMAN (1-136): 6.5e-61: 185: 99.27