HitPredict

Interactor 1: ML12B (O14950)
Myosin regulatory light chain 12B (MLC-2A) (MLC-2) (Myosin regulatory light chain 2-B, smooth muscle isoform) (Myosin regulatory light chain 20 kDa) (MLC20) (Myosin regulatory light chain MRLC2) (SHUJUN-1)
Gene: MYL12B

Interactor 2: LRRF2 (Q9Y608)
Leucine-rich repeat flightless-interacting protein 2 (LRR FLII-interacting protein 2)
Gene: LRRFIP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 172 Hs			1 721
+	Hs
		618753 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		LRRF2_HUMAN (1-721): 4.32e-103: 333: 100.00
+	Dm
		823809 SQH_DROME (1-172): 1.45e-61: 189: 81.03		Q9VXN3_DROME (355-718): 2.46e-61: 212: 33.97
+	Hs
		618695 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		LRRF1_HUMAN (280-458): 7.46e-52: 195: 56.35
+	Hs
		618698 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		MRCKA_HUMAN (231-721): 3.33e-32: 136: 12.06
+	Hs
		169065 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MYH10_HUMAN (222-720): 2.23e-18: 92.6: 11.91
+	Hs
		666741 MYL9_HUMAN (1-172): 2.2e-66: 201: 93.02		MYH10_HUMAN (222-720): 2.23e-18: 92.6: 11.91
+	Hs
		618654 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		MYH10_HUMAN (222-720): 2.23e-18: 92.6: 11.91
+	Hs
		169045 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MYH7_HUMAN (357-721): 9.48e-15: 80.6: 14.63
+	Mm
		1223376 Q6ZWQ9_MOUSE (1-172): 7.04e-67: 203: 97.67		MYH10_MOUSE (222-642): 2.07e-14: 79.5: 8.90
+	Hs
		169126 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		618717 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		MY18A_HUMAN (332-715): 3.37e-12: 72.4: 11.16
+	Hs
		169165 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MYH15_HUMAN (273-691): 1.59e-10: 66.9: 10.93
+	Hs
		169066 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MYH11_HUMAN (419-721): 4.38e-10: 65.6: 12.21
+	Hs
		169115 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MY18B_HUMAN (229-617): 1.08e-09: 64.2: 11.46
+	Hs
		169064 ML12B_HUMAN (1-172): 1.28e-67: 204: 100.00		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		618655 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		MYH11_HUMAN (419-721): 4.38e-10: 65.6: 12.21
+	Hs
		666740 MYL9_HUMAN (1-172): 2.2e-66: 201: 93.02		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Dm
		823778 SQH_DROME (1-172): 1.45e-61: 189: 81.03		MYSN_DROME (310-715): 1.23e-12: 73.9: 12.62
+	Hs
		618653 ML12A_HUMAN (15-172): 1.81e-65: 199: 99.37		MYH9_HUMAN (417-721): 3.17e-09: 62.9: 13.12
+	Hs
		533985 MLRV_HUMAN (9-166): 1.99e-54: 171: 57.23		MYH1_HUMAN (220-650): 1.15e-12: 74.1: 8.78