HitPredict

Interactor 1: GAK (O14976)
Cyclin-G-associated kinase (EC 2.7.11.1) (DnaJ homolog subfamily C member 26)
Gene: GAK

Interactor 2: DAPP1 (Q9UN19)
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (hDAPP1) (B lymphocyte adapter protein Bam32) (B-cell adapter molecule of 32 kDa)
Gene: DAPP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~Pkinase
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1311 Hs			1 280
+	Hs
		463219 SIK2_HUMAN (31-936): 2.02e-171: 536: 15.55		YES_HUMAN (4-280): 1.04e-56: 192: 19.80
+	Hs
		557345 TENS3_HUMAN (402-1221): 8.25e-151: 494: 20.28		SRC_HUMAN (4-280): 1.33e-56: 191: 18.77
+	Hs
		222200 SIK2_HUMAN (31-936): 2.02e-171: 536: 15.55		NCK2_HUMAN (6-129): 4.73e-41: 147: 28.00
+	Hs
		834199 TENS3_HUMAN (402-1221): 8.25e-151: 494: 20.28		CSK_HUMAN (10-280): 9.76e-42: 150: 13.43
+	Rn
		236503 PTEN_RAT (396-779): 1.44e-100: 328: 24.14		SRC_RAT (4-280): 1.06e-56: 192: 18.77
+	Hs
		463039 PTEN_HUMAN (396-779): 2.95e-100: 327: 24.14		YES_HUMAN (4-280): 1.04e-56: 192: 19.80
+	Hs
		841002 PTEN_HUMAN (396-779): 2.95e-100: 327: 24.14		FRK_HUMAN (3-280): 1.08e-52: 180: 19.38
+	Hs
		486692 KCC2B_HUMAN (40-430): 5.64e-91: 310: 22.70		FGR_HUMAN (4-280): 5.69e-55: 187: 18.43
+	Rn
		236499 PTEN_RAT (396-779): 1.44e-100: 328: 24.14		CSK_RAT (10-280): 5.62e-45: 159: 15.14
+	Hs
		951858 PTEN_HUMAN (396-779): 2.95e-100: 327: 24.14		PKHA1_HUMAN (128-254): 1.45e-34: 130: 31.11
+	Hs
		362385 BMP2K_HUMAN (35-311): 2.29e-41: 168: 41.79		ABL1_HUMAN (8-280): 4.15e-50: 179: 17.61
+	Hs
		72390 BMP2K_HUMAN (35-311): 2.29e-41: 168: 41.79		A9UF07_HUMAN (8-280): 1.87e-48: 174: 16.55
+	Hs
		463600 TPTE2_HUMAN (407-558): 8.9e-30: 127: 39.75		LYN_HUMAN (3-280): 7.93e-55: 186: 18.03
+	Ce
		111079 SEL5_CAEEL (30-333): 2.45e-36: 152: 37.54		Q95PW9_CAEEL (10-131): 2.69e-43: 153: 33.61
+	Hs
		291761 STK16_HUMAN (46-316): 3.33e-29: 121: 30.50		CSK_HUMAN (10-280): 9.76e-42: 150: 13.43
+	Hs
		440737 TENS1_HUMAN (513-1199): 7.16e-13: 75.7: 11.26		FYN_HUMAN (4-280): 3.63e-56: 190: 19.80
+	Hs
		1053727 NEK1_HUMAN (37-312): 1.72e-26: 120: 31.94		PTN11_HUMAN (35-225): 1.7e-29: 118: 22.28
+	Hs
		834232 TENS1_HUMAN (513-1199): 7.16e-13: 75.7: 11.26		CSK_HUMAN (10-280): 9.76e-42: 150: 13.43
+	Hs
		834197 TENS2_HUMAN (799-1197): 6.61e-11: 69.5: 14.70		CSK_HUMAN (10-280): 9.76e-42: 150: 13.43