HitPredict

Interactor 1: HDAC3 (O15379)
Histone deacetylase 3 (HD3) (EC 3.5.1.98) (Protein deacetylase HDAC3) (EC 3.5.1.-) (Protein deacylase HDAC3) (EC 3.5.1.-) (RPD3-2) (SMAP45)
Gene: HDAC3

Interactor 2: DDX17 (Q92841)
Probable ATP-dependent RNA helicase DDX17 (EC 3.6.4.13) (DEAD box protein 17) (DEAD box protein p72) (DEAD box protein p82) (RNA-dependent helicase p72)
Gene: DDX17

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	20663877, 19995069
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 428 Hs			1 729
+	Hs
		1038593 HDAC1_HUMAN (3-385): 0: 588: 62.92		DDX17_HUMAN (1-717): 0: 626: 100.00
+	Hs
		1270350 HDAC2_HUMAN (3-422): 0: 580: 58.63		DDX17_HUMAN (1-717): 0: 626: 100.00
+	Hs
		177186 HDAC3_HUMAN (1-428): 0: 600: 100.00		DDX5_HUMAN (82-715): 6.38e-164: 487: 66.41
+	Hs
		571439 HDAC1_HUMAN (3-385): 0: 588: 62.92		DDX5_HUMAN (82-715): 6.38e-164: 487: 66.41
+	Hs
		571532 HDAC2_HUMAN (3-422): 0: 580: 58.63		DDX5_HUMAN (82-715): 6.38e-164: 487: 66.41
+	Hs
		134143 HDAC2_HUMAN (3-422): 0: 580: 58.63		DDX3X_HUMAN (22-581): 1.42e-142: 434: 37.06
+	Hs
		1271686 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		DDX17_HUMAN (1-717): 0: 626: 100.00
+	Hs
		1198606 HDAC2_HUMAN (3-422): 0: 580: 58.63		DDX53_HUMAN (119-554): 1.9e-105: 337: 43.60
+	Hs
		571620 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		DDX5_HUMAN (82-715): 6.38e-164: 487: 66.41
+	Hs
		134234 HDAC6_HUMAN (5-320): 3.49e-103: 333: 23.24		DDX3X_HUMAN (22-581): 1.42e-142: 434: 37.06