Interactor 1: SOCS1 (O15524)
Suppressor of cytokine signaling 1 (SOCS-1) (JAK-binding protein) (JAB) (STAT-induced STAT inhibitor 1) (SSI-1) (Tec-interacting protein 3) (TIP-3)
Gene: SOCS1
Interactor 2: GHR (P10912)
Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]
Gene: GHR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10585430 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | SH2~fn3 |
| Common GO terms | GO:0005829 - cytosol GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0019221 - cytokine-mediated signaling pathway GO:0019901 - protein kinase binding GO:0036464 - cytoplasmic ribonucleoprotein granule |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
