Interactor 1: PER1 (O35973)
Period circadian protein homolog 1 (mPER1) (Circadian clock protein PERIOD 1) (Circadian pacemaker protein Rigui)
Gene: PER1

Interactor 2: CRY2 (Q9R194)
Cryptochrome-2
Gene: CRY2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.814

The method score is based on:

Property Details
Experiments 14701732, 24737000, 23555304
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains DNA_photolyase~Period_C, FAD_binding_7~Period_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
and 8 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1291
Mm

1 592
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024