HitPredict

Interactor 1: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Interactor 2: CSTF1 (Q05048)
Cleavage stimulation factor subunit 1 (CF-1 50 kDa subunit) (Cleavage stimulation factor 50 kDa subunit) (CSTF 50 kDa subunit) (CstF-50)
Gene: CSTF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	35509820, 35256949
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 465 Hs			1 431
+	Hs
		226765 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		LIS1_HUMAN (136-429): 9.55e-76: 243: 19.81
+	Hs
		227054 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		228612 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TBL1R_HUMAN (4-293): 1.29e-53: 188: 12.68
+	Hs
		228868 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		NLE1_HUMAN (247-429): 1.25e-46: 169: 18.48
+	Hs
		227617 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SMU1_HUMAN (253-429): 5.21e-28: 117: 19.02
+	Hs
		228315 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Hs
		228276 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75
+	Hs
		196917 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRP4_HUMAN (305-429): 8.1e-15: 78.2: 20.47
+	Hs
		229055 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		PRP19_HUMAN (136-335): 3.89e-14: 76.3: 24.50
+	Hs
		227540 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		TAF5_HUMAN (119-338): 1.63e-09: 62: 24.24
+	Hs
		228555 PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00		KTNB1_HUMAN (228-424): 7.27e-09: 59.7: 27.72
+	Hs
		1219356 CUL9_HUMAN (30-463): 1.19e-80: 274: 18.58		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Hs
		1281514 ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75
+	Hs
		475563 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		WDR5_HUMAN (2-289): 2.37e-58: 196: 17.75
+	Hs
		475845 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SMU1_HUMAN (253-429): 5.21e-28: 117: 19.02
+	Hs
		476181 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		SNR40_HUMAN (3-195): 1.23e-28: 117: 19.50
+	Hs
		476151 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		FBXW7_HUMAN (2-196): 3e-19: 92.1: 12.75
+	Hs
		196947 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRP4_HUMAN (305-429): 8.1e-15: 78.2: 20.47
+	Hs
		476564 UBC_HUMAN (1-77): 1.15e-29: 124: 32.47		PRP19_HUMAN (136-335): 3.89e-14: 76.3: 24.50