HitPredict

Interactor 1: WDR1 (O75083)
WD repeat-containing protein 1 (Actin-interacting protein 1) (AIP1) (NORI-1)
Gene: WDR1

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 606 Hs			1 454
+	Hs
		371880 TBL3_HUMAN (241-604): 3.26e-44: 170: 12.76		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		371397 LIS1_HUMAN (356-605): 2.62e-38: 148: 15.07		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		372767 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		373290 NLE1_HUMAN (480-605): 9.64e-33: 133: 22.73		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Mm
		373704 FBXW7_MOUSE (262-604): 9.71e-34: 138: 16.91		MYC_MOUSE (1-454): 1.16e-117: 353: 89.01
+	Hs
		373500 WDR3_HUMAN (407-606): 4.89e-30: 128: 21.57		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		371643 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		372177 SMU1_HUMAN (180-472): 5.95e-12: 70.5: 24.92		MYC_HUMAN (1-454): 4.53e-121: 362: 100.00
+	Hs
		406466 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		406801 WDR3_HUMAN (407-606): 4.89e-30: 128: 21.57		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Hs
		405975 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		MYCN_HUMAN (12-451): 8.07e-58: 199: 33.40
+	Mm
		1189859 FBXW7_MOUSE (262-604): 9.71e-34: 138: 16.91		SRBP2_MOUSE (124-446): 1.15e-36: 145: 13.60
+	Mm
		1353851 FBXW7_MOUSE (262-604): 9.71e-34: 138: 16.91		SRBP1_MOUSE (172-453): 7.23e-35: 140: 16.61
+	Hs
		787890 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		SRBP1_HUMAN (95-453): 7.2e-33: 134: 16.19
+	Hs
		1155134 WDR3_HUMAN (407-606): 4.89e-30: 128: 21.57		USF2_HUMAN (180-454): 2.9e-34: 133: 15.99
+	Hs
		959629 FBXW7_HUMAN (262-604): 2.82e-33: 137: 16.91		MAX_HUMAN (354-454): 1.4e-24: 101: 32.67
+	Hs
		648344 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		USF1_HUMAN (175-453): 3.38e-39: 145: 18.06
+	Hs
		965076 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		MGAP_HUMAN (151-449): 2.43e-27: 118: 17.71
+	Mm
		704106 WDR5_MOUSE (524-605): 5.38e-17: 84.3: 25.30		MAX_MOUSE (354-454): 3.61e-25: 102: 32.67
+	Hs
		959549 WDR5_HUMAN (524-605): 5.38e-17: 84.3: 25.30		MAX_HUMAN (354-454): 1.4e-24: 101: 32.67