HitPredict

Interactor 1: XPOT (O94258)
Exportin-T (Exportin(tRNA)) (Karyopherin-beta) (tRNA exportin)
Gene: los1

Interactor 2: SPI1 (P28748)
GTP-binding nuclear protein spi1
Gene: SPI1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	26771498
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Exportin-T~Ras, Ras~Xpo1
Common GO terms	GO:0005525 - GTP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 978 Sp			1 216
+	Hs
		162599 XPO1_HUMAN (1-977): 0: 555: 12.06		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		207921 XPOT_HUMAN (7-974): 1.15e-145: 459: 26.27		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Sc
		675912 XPO1_YEAST (1-975): 1.3e-143: 457: 12.22		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Hs
		919228 XPO6_HUMAN (2-974): 2.39e-129: 420: 10.60		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		919198 TNPO1_HUMAN (17-932): 3.15e-130: 417: 11.55		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		155560 TNPO2_HUMAN (17-928): 7.26e-126: 405: 10.86		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Dm
		1373317 Q9VRV8_DROME (2-928): 9.28e-118: 383: 10.33		RANL_DROME (3-216): 7.85e-90: 265: 59.26
+	At
		784988 TNPO1_ARATH (3-935): 4.13e-109: 360: 10.65		RAN1_ARATH (2-213): 1.18e-95: 279: 75.00
+	Hs
		297168 IPO13_HUMAN (1-969): 1.62e-107: 358: 13.40		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	At
		784987 MOS14_ARATH (1-952): 1.37e-99: 336: 12.10		RAN1_ARATH (2-213): 1.18e-95: 279: 75.00
+	Sc
		698996 MTR10_YEAST (1-910): 7.82e-105: 351: 14.59		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Hs
		919273 XPO5_HUMAN (4-665): 6.65e-103: 350: 15.77		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Sc
		698755 XPOT_YEAST (3-976): 3.38e-99: 338: 22.23		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22
+	Sc
		699022 MTR10_YEAST (1-910): 7.82e-105: 351: 14.59		GSP2_YEAST (1-216): 5.96e-81: 242: 86.82
+	Sc
		699000 XPOT_YEAST (3-976): 3.38e-99: 338: 22.23		GSP2_YEAST (1-216): 5.96e-81: 242: 86.82
+	Hs
		914368 XPO5_HUMAN (4-665): 6.65e-103: 350: 15.77		RB11A_HUMAN (3-207): 2.13e-74: 225: 24.76
+	Hs
		919299 IPO11_HUMAN (1-898): 1.44e-87: 303: 10.33		RAN_HUMAN (2-213): 1.56e-87: 258: 81.60
+	Hs
		207913 XPOT_HUMAN (7-974): 1.15e-145: 459: 26.27		RAB9A_HUMAN (10-172): 5.78e-25: 98.6: 29.41
+	At
		784985 HASTY_ARATH (2-643): 1.09e-20: 100: 12.40		RAN1_ARATH (2-213): 1.18e-95: 279: 75.00
+	Sc
		698877 MSN5_YEAST (3-445): 9.11e-16: 84.5: 12.02		GSP1_YEAST (1-216): 6.2e-87: 257: 87.22