HitPredict

Interactor 1: POF11 (Q09855)
F-box/WD repeat-containing protein pof11 (Meiotically up-regulated gene 156 protein)
Gene: POF11

Interactor 2: SKP1 (Q9Y709)
Suppressor of kinetochore protein 1 (P19/Skp1 homolog)
Gene: SKP1

Species: Schizosaccharomyces pombe 972h-

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15147268
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	F-box-like~Skp1, Skp1~WD40
Common GO terms	GO:0005829 - cytosol GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 506 Sp			1 161
+	Dm
		305542 FBXW7_DROME (37-505): 9.73e-103: 336: 22.11		O77430_DROME (1-161): 5.19e-78: 230: 56.71
+	Hs
		992212 FBW10_HUMAN (42-494): 7.2e-90: 298: 20.94		SKP1_HUMAN (1-161): 9.03e-82: 240: 55.76
+	Mm
		1353852 FBXW7_MOUSE (246-505): 4.06e-78: 260: 29.89		SKP1_MOUSE (1-161): 8.46e-82: 240: 55.76
+	Hs
		992290 FBXW7_HUMAN (246-505): 1.23e-77: 259: 29.89		SKP1_HUMAN (1-161): 9.03e-82: 240: 55.76
+	Ce
		111145 SEL10_CAEEL (79-410): 1.78e-54: 194: 20.18		SKR1_CAEEL (3-160): 1.71e-78: 232: 56.10
+	Sp
		1017865 POF1_SCHPO (328-506): 3.28e-44: 166: 24.86		SKP1_SCHPO (1-161): 4.52e-81: 238: 100.00
+	Hs
		992399 FBW1A_HUMAN (329-505): 3.07e-42: 160: 24.02		SKP1_HUMAN (1-161): 9.03e-82: 240: 55.76
+	Mm
		1190510 FBW1A_MOUSE (329-505): 1.1e-41: 159: 24.02		SKP1_MOUSE (1-161): 8.46e-82: 240: 55.76
+	Xl
		1259301 TRCB_XENLA (329-505): 8.2e-42: 158: 23.46		SKP1_XENLA (1-161): 9.03e-82: 240: 55.76
+	Mm
		1210439 FBW1B_MOUSE (329-505): 3.32e-41: 157: 20.11		SKP1_MOUSE (1-161): 8.46e-82: 240: 55.76
+	Hs
		992384 FBW1B_HUMAN (329-505): 3.1e-41: 157: 20.67		SKP1_HUMAN (1-161): 9.03e-82: 240: 55.76
+	Dm
		232056 O44382_DROME (329-505): 2.69e-42: 159: 22.91		O77430_DROME (1-161): 5.19e-78: 230: 56.71
+	Dm
		305505 Q9VDE3_DROME (329-505): 4.82e-42: 158: 22.91		O77430_DROME (1-161): 5.19e-78: 230: 56.71
+	Dm
		1267182 Q9VDE3_DROME (329-505): 4.82e-42: 158: 22.91		Q7KJ69_DROME (1-161): 4.37e-74: 220: 53.37
+	Hs
		261394 TBL1X_HUMAN (16-332): 3.75e-33: 134: 13.03		SKP1_HUMAN (1-161): 9.03e-82: 240: 55.76
+	Sc
		809273 MET30_YEAST (331-506): 1.01e-43: 165: 23.60		SKP1_YEAST (2-161): 5.58e-66: 201: 50.00
+	Ce
		111663 LIN23_CAEEL (329-505): 5.99e-40: 155: 22.91		G5EDD8_CAEEL (3-160): 3.14e-67: 203: 46.34
+	Dm
		1471477 Q9VDE3_DROME (329-505): 4.82e-42: 158: 22.91		Q9VWC4_DROME (2-151): 2.31e-65: 198: 47.71
+	Sp
		153337 POP2_SCHPO (432-506): 4.28e-10: 64.2: 18.67		SKP1_SCHPO (1-161): 4.52e-81: 238: 100.00
+	Sc
		460737 CDC4_YEAST (424-506): 3.02e-15: 80.7: 18.82		SKP1_YEAST (2-161): 5.58e-66: 201: 50.00