HitPredict

Interactor 1: PSA2 (O94579)
Probable proteasome subunit alpha type-2
Gene: pre8

Interactor 2: RPN6 (Q9P7S2)
Probable 26S proteasome regulatory subunit rpn6
Gene: RPN6

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22187461
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	Proteasome~RPN6_N
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Sp			1 421
+	Dm
		821845 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSD11_DROME (1-419): 5.23e-105: 319: 52.61
+	Hs
		127885 PSA5_HUMAN (3-245): 6.13e-93: 274: 34.27		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Dm
		1267331 PSA5_DROME (3-245): 1.32e-92: 273: 30.80		PSD11_DROME (1-419): 5.23e-105: 319: 52.61
+	Hs
		127881 PSA4_HUMAN (1-242): 2.16e-89: 266: 36.59		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Hs
		127916 PSA6_HUMAN (2-245): 4.52e-89: 265: 32.26		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Hs
		127880 PSA2_HUMAN (3-245): 1.25e-88: 263: 60.49		PSD11_HUMAN (1-419): 1.16e-106: 323: 53.79
+	Dm
		821875 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		PSMD6_DROME (27-419): 1.74e-81: 257: 13.86
+	Hs
		954777 PSA6_HUMAN (2-245): 4.52e-89: 265: 32.26		CSN2_HUMAN (11-417): 4.2e-94: 291: 20.53
+	Sc
		661575 PSA2_YEAST (1-245): 7.14e-90: 267: 66.40		RPN6_YEAST (4-419): 1.41e-90: 282: 47.55
+	Hs
		700640 PSA5_HUMAN (3-245): 6.13e-93: 274: 34.27		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		681648 PSA4_HUMAN (1-242): 2.16e-89: 266: 36.59		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		954813 PSA6_HUMAN (2-245): 4.52e-89: 265: 32.26		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Hs
		128155 PSA5_HUMAN (3-245): 6.13e-93: 274: 34.27		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Hs
		681166 PSA2_HUMAN (3-245): 1.25e-88: 263: 60.49		PSMD6_HUMAN (25-419): 1.4e-87: 273: 14.53
+	Dm
		1376916 PSA5_DROME (3-245): 1.32e-92: 273: 30.80		PSMD6_DROME (27-419): 1.74e-81: 257: 13.86
+	Hs
		128151 PSA4_HUMAN (1-242): 2.16e-89: 266: 36.59		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Hs
		128192 PSA6_HUMAN (2-245): 4.52e-89: 265: 32.26		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Hs
		128149 PSA2_HUMAN (3-245): 1.25e-88: 263: 60.49		PSD12_HUMAN (7-420): 7.07e-83: 263: 12.70
+	Dm
		821874 PSA2_DROME (2-245): 1.12e-103: 301: 58.20		CSN4_DROME (50-413): 1.59e-66: 219: 15.13
+	Hs
		954800 PSA6_HUMAN (2-245): 4.52e-89: 265: 32.26		CSN1_HUMAN (11-419): 6.03e-72: 235: 12.09